MRIで治療経過を観察し得た悪性リンパ腫肝浸潤の一例

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A case of malignant lymphoma with liver involvement is presented. A 48-year-old male patient was referred to our hospital for evaluation of incidentally found liver tumor. US-guided percutaneous liver biopsy proved the diagnosis of diffuse large cell type non-Hodgkin's lymphoma. Biopsy specimen from the right axillary lymph node showed the same histological findings, indicating the stage IV disease according to Ann Arbor classification. Combined chemotherapy produced remission of the tumor. Various imaging procedures, including US, CT,<SUP>67</SUP>Ga scintigraphy, and MRI, were performed before and after treatment. Hepatic tumor was most prominently demonstrated on T2-weighted MR image. T2-weighted MR image showed most characteristic changes during the treatment: Reappearance of hepatic vascular structures and normalization of previous strong intensity area were considered to reflect tumor-cidal effect of the regimen. MRI is considered an adequate imaging method for diagnosis, staging, and evaluation of therapy in hepatic lymphoma.
Kinki Brain Tumor Pathology Conferenceの論文