肝細胞癌に対する内科的局所熱凝固療法の長期予後について

概要

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We analyzed the rates of survival and local recurrence among 89 patients with solitary hepatocellular carcinoma (HCC) who underwent thermal ablation therapies as primary treatment (naive patients). The number of patients was as follows; 35 cases in percutaneous radiofrequency ablation (RFA), 5 in laparoscopic RFA, 22 in percutaneous microwave coagulation therapy (MCT), and 54 in laparoscopic MCT. Five-year local recurrence rates were 40%, 50%, 50%, and 18% in percutaneous RFA, laparoscopic RFA, percutaneous MCT, and laparoscopic MCT, respectively, with no statistical significance. Rates of 5-year survival were 78%, 75%, 82%, and 70% in percutaneous RFA, laparoscopic RFA, percutaneous MCT, and laparoscopic MCT, respectively, with no statistical significance.Thus, percutaneous RFA, laparoscopic RFA, percutaneous MCT, and laparoscopic MCT had same effectiveness for the local treatment of HCC.