ソナゾイド®造影エコー導入による当科での肝細胞癌局所治療の変化

概要

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Objective: We evaluate the usefulness of Sonazoid®-enhanced ultrasonography for nonsurgical local treatment for hepatocellular carcinoma (HCC).Materials and Methods: We have performed Sonazoid®-enhanced ultrasonography for liver tumors since May 2007. We treated 82 HCC nodules from January 2006 to April 2007 without Sonazoid®-utilization and 97 HCC nodules from May 2007 to April 2009 with Sonazoid®-utilization. We examined the detectability of HCC and efficacy of treatment in each period.Results: Eleven nodules (13.2%) and 3 nodules (3.1%) were undetectable by ultrasonography before and after Sonazoid®-utilization, respectively (p = 0.012). Residual tumor after local treatment existed in 7 of 71 nodules (9.9%) and 6 of 90 nodules (6.6%) before and after Sonazoid®-utilization, respectively (p = 0.112).Conclusion: Sonazoid®-enhanced ultrasonography is a useful technique in treatment of HCC.