Changes in liver and spleen volume in various types of compensated liver cirrhosis. Measurement by computed tomography.:measurement by computed tomography

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Liver and spleen volume were measured by computed tomography in 8 healthy voluneteers and in 21 patients of various types of compensated liver cirrhosis. Patients were divided into 3 groups (8 of viral group, 6 of alcoholic group and 6 of combined group) according to the histopathological findings of the liver and also according to the history of blood transfusion, HBs-Ag and alcohol drinking habit. Each volume was calculated by adding together the area measurements obtained from successive transverse abdominal scans. In the liver volume (mean±S.E.) alcoholic group (1381±86cm3) was significantly larger than the healthy volunteers (1027±27cm3) (p<0.0008), viral group (887±79cm3) (p<0.001) and combined group (1067±69cm3) (p<0.01) respectively. In the spleen volume, alcoholic group (158±21 cm3) was significantly larger than the healthy volunteers (84±4.7cm3) (p<0.02). Concerning the liver cell size, alcoholic group (395±23cm2) was significantly larger than the viral group (302±10um2) (p<0.006). Combined group (390±38um2) was also significantly larger than viral group (p<0.04).
財団法人日本消化器病学会の論文