The incidence of palmar erythema in patients with alcoholic fatty liver. A comparative study with fatty liver of other origin.:A Comparative Study with Fatty Liver of Other Origin

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The incidence of palmar erythema was studied in 43 patients who had histologically proven fatty liver with negative HBs-Ag and without history of blood transfusion, acute hepatitis nor jaundice. Incidence of palmar erythema in 17 patients with alcoholic fatty liver was so high as 82% (14 out of 17), and that in alcoholic fatty liver accompanied by obesity or diabetes mellitus was 71% (5 out of 7). In contrast, the incidence in 19 fatty liver patients without ethanol intake was as low as 16%. Significant difference (P<0.005) was found between alcoholic fatty liver group and the fatty liver group without ethanol intake. Also significant difference (P<0.025) was found between alcoholic fatty liver group accompanied by obesity or diabetes mellitus and the group without ethanol intake. The estrogen levels in serum and urines estimated in five patients with alcoholic fatty liver and palmar erythema proved to be in normal range. Malnutrition did not exist in those patients with alcoholic fatty liver.Hence, it is concluded that high incidence of palmar erythema in alcoholic fatty liver may be associated with direct effect of ethanol on the vasculature.
財団法人日本消化器病学会の論文