Allosamidin, a chitinase inhibitor produced by Streptomyces, acts as an inducer of chitinase production in its producing strain
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概要
- 論文の詳細を見る
Allosamidin is a chitinase inhibitor produced by Streptomyces. Allosamidin-producing Streptomyces is frequently found in soil. Allosamidin is a hydrophilic compound, but is found only in mycelia of its producer, and exogenous allosamidin is adsorbed on mycelia of its producing strain. We found that exogenous addition of allosamidin to a culture medium with colloidal chitin as a sole carbon source can strongly accelerate the chitinase production by an allosamidin-producing Streptomyces at low concentrations such as 1 μM. On the other hand, allosamidin depressed the chitinase activity in the culture of Streptomyces lividans, an allosamidin-nonproducing microbe. These results suggest that allosamidin has a physiological role in its producer as an inducer of chitinase production, which may be useful for chitin utilization by the producer in chitin-rich environment such as in soil.
- Japan Academy,日本学士院の論文
著者
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Nagasawa Hiromichi
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The U
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Matsuura hiroshi
Department of Physiology, Shiga University of Medical Science
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SAKUDA Shohei
Department of Applied Biological Chemistry, University of Tokyo
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OKAMOTO SUSUMU
Department of Internal Medicine, Division of Gastroenterology and Hepatology, Keio University School
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Sakuda Shohei
Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Uni
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Matsuura Hiroshi
Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Uni
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Okamoto Shigehisa
Department Of Agricultural Science Kagoshima University
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Nagasawa Hiromichi
Graduate School Of Agricultural And Life Sciences University Of Tokyo
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Nagasawa Hiromichi
Department Of Agricultural Chemistry Faculty Of Agriculture The University Of Tokyo
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Nagasawa Hiromichi
Department Of Applied Biological Chmistry Graduate School Of Agricultural And Life Sciences The Univ
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Okamoto Susumu
Department Of Agricultural Chemistry Tottori University:(present Address)department Of Fermentation
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作田 庄平
東大 大学院
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NAKANISHI Eiyu
Department of Applied Biological Chemistry, The University of Tokyo
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Matsuura H
Ntt Serv. Integration Lab. Musashino‐shi Jpn
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Nakanishi Eiyu
Department Of Applied Biological Chemistry The University Of Tokyo
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OKAMOTO Susumu
Department of Applied Biological Chemistry, The University of Tokyo
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SAKUDA Shohei
Department of Agricultural Chemistry, The University of Tokyo
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