A Case of Malignant Lymphoma with Hemophagocytic Syndrome Presenting as Hepatic Failure.
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概要
- 論文の詳細を見る
We report the case of a 50-year-old female with malignant lymphoma presenting hemophagocytic syndrome and liver failure. She developed high fever, marked jaundice, and progressive liver failure, followed by evidence of disseminated intravascuiar coagulation (DIC). The course was complicated by severe hepatitis and the patient died six days after admission. Pathological diagnosis on autopsy specimens of the lung hilar lymph nodes was non-Hodgkin's T cell lymphoma, of the diffuse small cell type. Histopathologic examination of the liver demonstrated diffuse liver cell destruction with prominent T lymphocyte infiltration in the portal and periportal area. In addition to marked lymphoma cell infiltration, hemophagocytosis by prominent infiltrative macrophages was observed in various organs, such as the liver and bone marrow, indicating the hemophagocytic syndrome. The emophagocytic syndrome characterized in the present case may have been responsible for the extremely rapid and fulminant course.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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SATA Michio
Department of Digestive Disease Information & Research
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Kojiro Masamichi
Department Of Gastroenterology And Hepatology Kinki University School Of Medicine
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Kumashiro Ryukichi
Department Of Gastroenterology Kurume University
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Arima Nobuyuki
Department Of Clinical Pathology Kumamoto City Hospital
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Sakisaka Shotaro
Department Of Gastroenterology And Hepatology Fukuoka University School Of Medicine
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HINO TERUKO
Department of Internal Medicine, Kurume University School of Medicine
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HINO TERUKO
Departments of Medicine Kurume University School of Medicine
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UCHIMURA YASUYO
Department of Medicine, Kurume University School of Medicine
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YOSHITAKE MASAO
Departments of Medicine Kurume University School of Medicine
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ARIMA NOBUYUKI
Departments of Medicine Kurume University School of Medicine
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NOUNO RYUICHI
Departments of Medicine Kurume University School of Medicine
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KOLA YURIKO
Departments of Medicine Kurume University School of Medicine
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TANIKAWA KYUICHI
Pathology, Kurume University School of Medicine
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UCHIMURA YASUYO
Departments of Medicine Kurume University School of Medicine
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KOJIRO MASAMICHI
Departments of Medicine Kurume University School of Medicine
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KUMASHIRO RYUKICHI
Departments of Medicine Kurume University School of Medicine
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