Thyroid Dysfunction Induced by Interferon Therapy for the Treatment of Hepatitis Type C. A Report of 4 Cases.:A Report of 4 Cases
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概要
- 論文の詳細を見る
We describe 4 patients with onset or aggravation of thyroid dysfunction induced by interferon (IFN) treatment of hepatitis type C. All 4 patients were females; 2 had hyperthyroidism and 2 had hypothyroidism during or after IFN therapy. The onset or aggravation of thyroid dysfunction occurred during administration of IFN in 1 patient and 4 weeks after the end of IFN therapy in the remaining 3 patients. The 2 patients who demonstrated hyperthyroidism were euthyroid and negative for thyroid autoantibodies before receiving IFN therapy. The remaining 2 patients who demonstrated hypothyroidism were positive for thyroid autoantibodies before IFN therapy. One of these patients had a slight decrease in thyroid function before IFN therapy. Anti-thyroid stimulating hormone (TSH) receptor antibodies became positive in all 4 patients. Since there may have been a causal relationship between IFN therapy and the onset or aggravation of thyroid dysfunction, IFN therapy should be administered with caution.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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SATA Michio
Department of Digestive Disease Information & Research
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Noguchi Seiji
Department Of Hepatology Osaka City University Graduate School Of Medicine
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Nakano Hitoshi
Department Of Electrical Engineering School Of Science & Engineering Kinki University
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Yamakawa Yosuke
Department Of Surgery Ii Nagoya City University Medical School
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Ide Tatsuya
Department Of Internal Medicine Kurume University School Of Medicine
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Tanikawa Kyuichi
Department Of Digestive Disease Information And Research Kurume University School Of Medicine
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NAKANO HITOSHI
Department of Medicine, Kurume University School of Medicine
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TOKESHI SHIGERU
Department of Medicine, Kurume University School of Medicine
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YAMAKAWA YOSUKE
Department of Medicine, Kurume University School of Medicine
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IDE Tatsuya
Department of Aerospace Engineering, Tokyo Metropolitan University
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