Incidence of Hepatitis D Virus Infection in Japanese Patients with Hepatocellular Carcinoma Immunohistochemical Investigation of the Delta Antigen.:Immunohistochemical Investigation of the Delta Antigen
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概要
- 論文の詳細を見る
In order to clarify the incidence of the delta agent among hepatocellular carcinomas (HCCs) in Kurume, where the hepatitis B infection and its related HCC are most prevalent in Japan, liver tissues from sero hepatitis B surface antigen-positive autopsy cases, with or without HCC, were immunohistochemically investigated for detection of the delta antigen. Only one patient (1.7%) among 58 patients with HCC was found to have deltaantigen in the nuclei in the hepatocytes, which were diffusely distributed throughout the non-cancerous liver. None of 26 patients with liver cirrhosis showed delta-antigen in the liver tissue. The incidence is so low that the delta agent is unlikely to have a role in the development of HCC in our areas.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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Kosai Kenichiro
Department of Cardiology Regeneration&Advanced medical Science, Graduate School of Medicine, Gifu Un
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Kojiro Masamichi
Department Of Gastroenterology And Hepatology Kinki University School Of Medicine
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NAKASHIMA OSAMU
Department of Pathology and Research Center of Innovative Cancer Therapy of the 21st Century COE Pro
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Shimamatsu Kazuhide
Department Of Pathology Yame General Hospital
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Yasunaga Masafumi
Department Of Anatomic Pathology Kyushu University Hospital
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Kage Masayoshi
Department Of Diagnostic Pathology Kurume University Hospital
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IHA HAYATO
Department of Pathology, Kurume University School of Medicine
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HARAMAKI MAKOTO
Department of Pathology, Kurume University School of Medicine
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SHIMAMATSU KAZUHIDE
Department of Pathology, Kurume University School of Medicine
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GOVINDARAJAN SUGANTHA
Department of Pathology, Rancho Los Amigos Hospital, University ofSouthern California
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