An In Vitro Chemosensitivity Test for Colorectal Cancer Using Collagen-gel Droplet Embedded Cultures.
スポンサーリンク
概要
- 論文の詳細を見る
This study evaluated in vitro assay for chemosensitivity test using a collagen-gel droplet embedded culture drug sensitivity test (CD-DST) for colorectal cancer. CD-DST was performed in 24 patients with Dukes B, C colorectal cancer. Primary cultures of tumor cell samples from 87.5% (21124) patients with colorectal cancer were successful. The efficacy rates assessed by CD-DST of five anticancer drugs evaluated were : 60.4% for adriamycin, 58.9% for etoposide, 56.7% for cisplatin, 53.4% for 5-fluorouracil, for 31.1% for mitomycin C, and 9.5% for vindesine. The present study demonstrated the clinical usefulness of CD-DST in evaluating the response to chemotherapy in colorectal cancer.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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Araki Yasumi
Department Of Surgery Kurume University Medical Center
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Yamauchi Ken
Department Of Electrical And Electronic Engineering Musashi Institute Of Technology
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ISOMOTO Hiroharu
Department of Surgery, Kurume University Medical Center
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Hayashi Katsumi
Department Of Gastroenterology Nagoya Daini Red Cross Hospital
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Yasunaga Masafumi
Department Of Anatomic Pathology Kyushu University Hospital
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Matsumoto Atsushi
Department Of Electric Engineering Hiroshima Institute Of Technology
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HAYASHI KATSUMI
Department of Surgery, Kurume University Medical Center
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KAIBARA ATSUSHI
Department of Surgery, Kurume University Medical center
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YATSUGI HIROYUKI
Department of Surgery, Kurume University Medical center
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Hayashi Katsumi
Department of Agricultural Chemistry, College of Agriculture, University of Osaka Prefecture
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