Polarographic study on the transportation of oxygen by perfluorocarbon emulsion as artificial blood.
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概要
- 論文の詳細を見る
Restrictive factors of oxygen release from dispersed particles of perfluorocarbon (PFC) in a form of emulsion have been studied by polarographic reduction currents of oxygen in the emulsion. The oxygen reduction currents in PFC emulsion in open system increased linearly with the volume fraction of PFC component, and were diffusion-controlled. The increase of current was ascribed to the increase of oxygen supply to the electrode from PFC particles in the emulsion. Analyzing the oxygen reduction current due to PFC particles, the ratio of diffusion coefficients of oxygen inside and outside PFC particle (<I>D</I><SUB>1</SUB>⁄<I>D</I><SUB>0</SUB>) and the oxygen partition coefficient between the both sides (<I>C</I><SUB>1</SUB>⁄<I>C</I><SUB>0</SUB>) were obtained. The release of oxygen from PFC particle was rate-determined by oxygen diffusion in the particle and the diffusion itself was determined by inner viscosity of PFC particle. The surfactant layer of PFC particle did not play any appreciable role such as permeability barrier for oxygen transportation.
- 公益社団法人 日本化学会の論文
著者
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Hayashi Katsumi
Department Of Gastroenterology Nagoya Daini Red Cross Hospital
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Takagi Masanosuke
Department o f Agricultural Chemistry, College o f Agriculture, University
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Hayashi Katsumi
Department of Agricultural Chemistry, College of Agriculture, University of Osaka Prefecture
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