Minute Lung Carcinoma Associated with Focal Honeycombed Lesion.

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概要

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• We report a case of minute lung carcinoma that developed in a focal honeycombed lesion in the right lung. A 70-year-old man presented hemosputum, and a cytological examination result was at class IV. A right lower lobectomy of the lung was performed. Microscopically, the thickened alveolar wall revealed tumor cells indicating a minute carcinoma, and showed squamous hyperplasia, metaplasia, and dysplasia, with the carcinoma in the distal airway epithelium. This peripheral lung carcinoma in a focal honeycombed lesion demonstrated the various stages of multistep carcinogenesis, which is recognized in hilar type squamous cell carcinoma. To date, the association between a honeycombed lesion and lung cancer has been poorly described. Here we have presented clear evidence of the association of this carcinoma with the honeycombed lesion.

• 久留米大学医学部 The Kurume Medical Journal 編集部の論文

著者

• NAKASHIMA OSAMU

  Department of Pathology and Research Center of Innovative Cancer Therapy of the 21st Century COE Pro

• Terazaki Yasuhiro

  Department Of Surgery Kurume University School Of Medicine

• Hayashi Akihiro

  Department Of Biotechnology Faculty Of Engineering Nagoya University

• Miwa Keisuke

  Department Of Medical Oncology Comprehensive Cancer Center Saitama Medical University

• Shirouzu Kazuo

  Department Of Surgery Kurume University

• Fukunaga Mari

  Department Of Surgery Kurume University School Of Medicine

• Takamori Shinzo

  Department Of Surgery

• Nakamura Hisashi

  Department Of Earth And Planetary Science The University Of Tokyo:frontier Research Center For Globa

• HAYASHI Akihiro

  Departments of Surgery, Kurume University School of Medicine

• SHIROUZU KAZUO

  Departments of Surgery, Kurume University School of Medicine

• MIWA KEISUKE

  Departments of Surgery, Kurume University School of Medicine

• TERAZAKI YASUHIRO

  Departments of Surgery, Kurume University School of Medicine

• SHIROUZU KAZUO

  Department of Gastroenterology and Surgery, Kurume University School of Medicine

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