Rapid-growth Lung Cancer Associated with a Pulmonary Giant Bulla: A Case Report
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概要
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A giant bulla of the lung is suggested as a risk factor for lung cancer. Here we report a case with lung cancer in a giant bulla, which showed rapid progression. A 57-year-old man, who had a history of heavy smoking, was admitted to our hospital due to hemoptysis. A chest X-ray revealed a giant bulla with a ground glass shadow and a high fluid level in the right upper lung. Sputum cytology was negative for malignant cells. A chest X-ray a month later showed increases of the size of the radio-opaque shadow and of the air-fluid retention, suggesting pulmonary hemorrhage from the giant bulla. Limited resection or lobectomy was indicated, but pneumonectomy was performed due to the severe air-leak. Macroscopically, a multiple nodular tumor arose from the bulla wall, which might be related to blood flow and necrotic tissue. The postoperative pathological diagnosis was papillary adenocarcinoma. Unfortunately, the patient developed a recurrence of carcinoma in the pleuroperitoneal cavity and died at 2.5 months after the operation. Based on this report and review of other cases in the literature, we should keep in mind the rapid progression of lung cancer in association with an emphysematous bulla.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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MATSUO TOSHIHIRO
Department of Artificial Joints & Biomaterials, Graduate School of Biomedical Sciences, Hiroshima Un
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Hayashi Akihiro
Department Of Biotechnology Faculty Of Engineering Nagoya University
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Miwa Keisuke
Department Of Medical Oncology Comprehensive Cancer Center Saitama Medical University
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Shirouzu Kazuo
Department Of Surgery Kurume University
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Maeshiro Kanetaka
Department Of Surgery Kurume University School Of Medicine
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Takamori Shinzo
Department Of Surgery
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Nakamura Hisashi
Department Of Earth And Planetary Science The University Of Tokyo:frontier Research Center For Globa
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FUKUNAGA MART
Department of Surgery, Kurume University School of Medicine
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SHIROUZU KAZUO
Department of Gastroenterology and Surgery, Kurume University School of Medicine
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