Quantitative Changes in Serum Concentration of Bovine Gut Chitinase in Theileria Infection

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概要

• 論文の詳細を見る

• Bovine gut chitinase is exclusively produced in the liver and secreted into the blood. In the present study, we established a semi-quantitative method by Western blot analysis for measurement of the chitinase content in blood and examined its alteration during postnatal development and experimental infection with hemoprotozoan parasite in cattle. Its serum levels from 1 week to 1 year of age showed a significant increase only in 3-4-month-old group. The plasma concentration of the gut chitinase was not changed during acute inflammation caused by lipopolysaccharide but increased gradually after a Theileria injection and peaked at 52 days post-infection. It appears that the increase in the blood chitinase levels might be a defensive response in cattle against protozoan infection.

• 公益社団法人 日本獣医学会の論文

著者

• ONUMA Misao

  Laboratory of Infectious Disease, Graduate School of Veterinary Medicine, Hokkaido University

• Onuma Misao

  Laboratorie Of Infectious Disease Graduate School Of Veterinary Medicine Hokkaido University

• Suzuki Masako

  Department Of Chemistry College Of Arts And Sciences Showa University

• Syuto Bunei

  Department Of Biochemistry Faculty Of Veterinary Medicine Hokkaido University

• Iwanaga Toshihiko

  Laboratories Of Anatomy Graduate School Of Veterinary Medicine Hokkaido University

• Kimura Kazuhiro

  Laboratorie Of Biochemistry Graduate School Of Veterinary Medicine Hokkaido University

• KIMURA Kazuhiro

  Laboratory of Biochemistry, Graduate School of Veterinary Medicine, Hokkaido University

• FUJIMOTO Wakako

  Laboratory of Histology and Cytology, Graduate School of Medicine, Hokkaido University

• SYUTO Bunei

  Department of Veterinary Medicine, Faculty of Agriculture, Iwate University

• SUZUKI Masako

  Department of Veterinary Medicine, Faculty of Agriculture, Iwate University

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