Full Genome Sequence and Virulence Analyses of the Recent Equine Isolate of Japanese Encephalitis Virus
スポンサーリンク
概要
- 論文の詳細を見る
In the past 25 years, there has been only one case of Japanese encephalitis in horses in Japan. We determined the full genome sequence of the Japanese encephalitis virus (JEV) strain JEV/eq/Tottori/2003 isolated from an afflicted horse and also analyzed its virulence in mice. The sequence analysis showed that the genome of JEV/eq/Tottori/2003 is similar to that of genotype I, a dominant genotype of JEV presently circulating in Japan. Its neurovirulence, but not neuroinvasiveness, was still as high as it was for genotype III, thus indicating the necessity for continuation of a vaccination program of horses against JEV.
著者
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Maeda Ken
Laboratory Of Veterinary Microbiology Faculty Of Agriculture Yamaguchi University
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Matsumura Tomio
Epizootic Research Center Equine Research Institute Jra
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Yamanaka Takashi
Epizootic Research Center Equine Research Institute Japan Racing Association
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KONDO Takashi
Epizootic Research Station, Equine Research Institute, Japan Racing Association
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SHIMOJIMA Masayuki
Laboratory of Veterinary Microbiology, Faculty of Agriculture, Yamaguchi University
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NAGAO Yumiko
Laboratory of Veterinary Microbiology, Faculty of Agriculture, Yamaguchi University
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SHIMODA Hiroshi
Laboratory of Veterinary Microbiology, Faculty of Agriculture, Yamaguchi University
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TAMARU Seiji
Laboratory of Veterinary Microbiology, Faculty of Agriculture, Yamaguchi University
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Kondo Takashi
Epizootic Research Center Equine Research Institute Japan Racing Association
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Maeda Ken
Laboratory Of Fisheries Biology & Coral Reef Studies Faculty Of Science University Of The Ryukyu
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