Seroepidemiology of Reovirus in Healthy Dogs in Six Prefectures in Japan

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概要

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• Reovirus infection is common in mammals. However, seroepidemiological data of reovirus neutralizing antibodies are limited in dogs. In this study, sera of 65 healthy dogs from six prefectures across Japan were tested for neutralizing antibodies against reovirus serotype 1 strain Lang (T1L), serotype 2 strain Amy (T2A) and serotype 3 strain Dearing (T3D) using plaque reduction neutralization test (PRNT). Seropositivity against reovirus T1L, T2A and T3D was 53.85%, 33.85% and 46.15%, respectively. Distribution of reovirus seropositive samples displayed no distinguishable geographical pattern. However, reovirus seropositivity increases with age and in dogs housed outdoor. Co-infection of multiple reovirus serotypes in dogs is also possible. These data will provide valuable insights towards the usage of reovirus in oncolytic virotherapy in canine cancers.

• 公益社団法人 日本獣医学会の論文

著者

• Maeda Ken

  Laboratory Of Fisheries Biology & Coral Reef Studies Faculty Of Science University Of The Ryukyu

• Mizuno Takuya

  Laboratories Of Veterinary Internal Medicine Dep. Of Veterinary Medicine Fac. Of Agriculture Yamaguchi Univ. ...

• OKUDA Masaru

  Laboratories of Veterinary Internal Medicine, Department of Veterinary Medicine, Faculty of Agriculture, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan

• HWANG Chung

  Laboratory of Veterinary Internal Medicine, The United Graduate School of Veterinary Science, Yamaguchi University

• MOCHIZUKI Masami

  Emerging Infectious Diseases, Joint Faculty of Veterinary Medicine, Kagoshima University

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• Seroepidemiology of Reovirus in Healthy Dogs in Six Prefectures in Japan

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