Apple Polyphenols Influence Cholesterol Metabolism in Healthy Subjects with Relatively High Body Mass Index
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概要
- 論文の詳細を見る
We performed a randomized double-blind, placebo-controlled study on moderately obese male and female subjects (71 subjects) with a body mass index ranging from 23 to 30 to evaluate the efficacy of 12-week intake of polyphenols extracted from apples and hop bract (600 mg/day). We confirmed that 12-week ingestion of polyphenol-containing capsules significantly decreased total cholesterol and LDL-cholesterol levels. The effects of the apple polyphenol-containing capsules were more marked than those of the hop bract polyphenol-containing capsules. The visceral fat area and the level of adiponectin in the group administered apple polyphenols improved in comparison with the control group. Blood and physical examinations revealed on clinical problems, and no adverse reactions were observed during the ingestion period. These results demonstrate that apple polyphenols regulate fat metabolism in healthy subjects with relatively high body mass index.
- 日本油化学会の論文
著者
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Kobayashi Tetsuyuki
Department of Biological Sciences, Graduate School of Humanities and Sciences, Ochanomizu University
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Kanda Tomomasa
Res. Laboratories For Fundamental Technol. Of Food Asahi Breweries Ltd.
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Ohtake Yasuyuki
Fundamental Research Laboratory Asahi Breweries Ltd.
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Shimasaki Hiroyuki
Department Of Biochemistry Teikyo University School Of Medicine
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Kanda Tomomasa
Fundamental Research Laboratory Asahi Breweries Limited
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Nagasako-Akazome Yoko
Fundamental Research Laboratory, Asahi Breweries, Ltd.
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NAGASAKO-AKAZOME Yoko
Fundamental Research Laboratory, Asahi Breweries Ltd.
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Kobayashi Tetsuyuki
Department of Biology, Ochanomizu University
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KANDA Tomomasa
Fundamental Research Laboratory, Asahi Breweries, Ltd.
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Ohtake Yasuyuki
Fundamental Research Laboratory, Asahi Breweries, Ltd.
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Shimasaki Hiroyuki
Department of Health and Nutrition, University of Arts and Sciences
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