2A2-N03 脂質ナノチューブを用いたナノピペット作製(ナノ・マイクロバイオシステム)

概要

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We propose a nano pipette with a lipid nanotube (LNT) as a nanochannel. Lipid nanotubes have multi lipid bilayer with a hollow cylindrical nano structure and their outer and inner surfaces are hydrophilic. Fabrication process of the LNT nano pipette is consisted of two processes; picking up and sealing processes. As picking up process, a single lipid nanotube is picked up inside micro glass pipette by use of micromanipulator. Then, as sealing process, the interspace between the lipid nanotube and the micro pipette is sealed with photo-crosslinkable resin. A lipid nanotube of the fabricated nano pipette is used as a nanochannel. The fluorescent solution was spouted by electroosmotic phenomenon from the LNT nano pipette. The nano pipette is effective to apply the minimal changes to the environment as an end-effecter for biological applications.
一般社団法人日本機械学会の論文
2007-05-11