T1501-2-4 マイクロ流路と磁気駆動マイクロツールを用いた微粒子の連続選別(マイクロ・ナノ技術のロボティクス応用(2))

概要

論文の詳細を見る
We succeeded in size-dependent continuous particle filtration and particle trap using magnetically driven microtool (MMT) and centrifugal force in a microfluidic chip. Novelties of this paper are summarized as follows. (1) Filtering efficiency was improved than filtration by solely centrifugal force by MMT rotation. (2) This filtration is robust against pressure fluctuation in a chip by mechanical particle separation using sidewalls. (3) Size-classified microparticles can be trapped in the microchannels and treated by reagent. Microparticles having different sizes flow in circular microchannels and separated according to their sizes by the graduated gaps between sidewall and bottom by centrifugal force. MMT is positioned inside the microchamber and rotated by external magnetic force. Rotation of MMT enhances the sorting efficiency. By flow control, size-classified microparticles can also be aligned in the circular microchannel and retrieved concurrently. We demonstrated filtration of the microparticles using 3D-MMT rotation and centrifugal force and trap of the size-classified microparticles in a chip.
社団法人日本機械学会の論文
2009-09-12