Aldose Reductase and Advanced Glycation Endproducts Inhibitory Effect of Phyllostachys nigra(Pharmacognosy)
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概要
- 論文の詳細を見る
To evaluate active principles for diabetic complications from the black bamboo leaves, Phyllostachys nigra, eight compounds were isolated and tested for their effects on rat lens aldose reductase and advanced glycation endproducts. As a result, luteolin 6-C-(6"-O-frans-caffeoylglucoside) was found to show a strong aldose reductase and advanced glycation endproducts inhibition. This compound showed antioxidative activity measured in Photochem^[○!R] apparatus. It is concluded, therefore, that luteolin 6-C-(6"-O-*ran,s-caffeoylglucoside) (6), a flavone of this plant, have antioxidative as well as aldose reductase and advanced glycation endproducts inhibitory effects. As a result, this compound could be offered as a leading compound for further study as a new natural products drug for diabetic complications.
- 社団法人日本薬学会の論文
- 2007-08-01
著者
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Jung Sang
Natural Products Research Center, Korea Institute of Science and Technology (KIST) Gangneung Institu
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Jung Sang
Natural Products Res. Center Korea Inst. Of Sci. And Technol. (kist) Gangneung Inst.
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Lee Eun
Natural Products Research Institute College Of Pharmacy Seoul National University
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Lee Jung
Natural Product Biosynthesis Research Unit Korea Research Institute Of Bioscience & Biotechnolog
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Jung Sang
Natural Products Research Center Korea Institute Of Science And Technology (kist) Gangneung Institut
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Lee Hee
Natural Products Res. Center Korea Inst. Of Sci. And Technol. Gangneung Inst.
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Lee Hee
Natural Products Research Center Korea Institute Of Science And Technology
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Kim Chul
Natural Products Res. Center Korea Inst. Of Sci. And Technol. Gangneung Inst.
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UM Byung
Natural Products Research Center, Korea Institute of Science and Technology (KIST) Gangneung Institu
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Um Byung
Natural Products Res. Center Korea Inst. Of Sci. And Technol. Gangneung Inst.
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Jung Sang
韓国
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Lee Hee
Natural Products Res. Center Gangneung Inst. Korea Inst. Of Sci. And Technol.
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Lee Eun
Natural Products Research Center Korea Institute Of Science And Technology (kist) Gangneung Institut
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Lee Jung
Natural Products Research Center Korea Institute Of Science And Technology (kist) Gangneung Institut
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Kim Chul
Natural Products Res. Center Gangneung Inst. Korea Inst. Of Sci. And Technol.
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