Plastoquinones from Sargassum yezoense; Chemical Structures and Effects on the Activation of Peroxisome Proliferator-Activated Receptor Gamma
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概要
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Four new plastoquinones, together with two known compounds, sargahydroquinoic acid and sargaquinoic acid, were isolated from the brown alga, Sargassum yezoense collected from the eastern coast of Korea. The structures of these compounds were elucidated based on spectroscopic analyses including NMR and MS. Their structures designated as meroterphenol A (1), B (2), C (3) and D (4) were characterized by a 6-methyl-1,4-benzohydroquinone moiety with an oxygenated diterpenoic acid chain. Meroterphenols A—D showed potent activation effects on peroxisome proliferator-activated receptor gamma (PPARγ).
著者
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Kim Hyung
Department of Internal Medicine, Seoul National University College of Medicine, Cardiovascular Labor
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Kim Hyung
Department Of Biochemistry Ewha Womans University School Of Medicine
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Kwon Hak
Natural Products Laboratory College Of Pharmacy Sung Kyun Kwan University
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KIM Min
Natural Products Research Center, Korea Institute of Science and Technology (KIST) Gangneung Institu
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UM Byung
Natural Products Research Center, Korea Institute of Science and Technology (KIST) Gangneung Institu
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Um Byung
Natural Products Res. Center Korea Inst. Of Sci. And Technol. Gangneung Inst.
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Kim Min
Natural Products Research Center Korea Institute Of Science And Technology (kist) Gangneung Institut
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Kim Su
Natural Products Research Center, Korea Institute of Science and Technology (KIST)
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Kim Min
Natural Products Res. Center Korea Inst. Of Sci. And Technol. (kist)
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Kwon Hak
Natural Products Research Center, Korea Institute of Science and Technology (KIST)
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Kim Hyung
Department of Biology, Kangnung National University
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Um Byung
Natural Products Research Center, Korea Institute of Science and Technology (KIST)
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Kim Min
Natural Products Research Center, Korea Institute of Science and Technology (KIST)
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Kwon Hak
Natural Medicine Center, Korea Institute of Science and Technology (KIST), Gangneung
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Kim Min
Natural Medicine Center, Korea Institute of Science and Technology (KIST), Gangneung
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