New Cytotoxic Butanolides from Lindera obtusiloba BLUME
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概要
- 論文の詳細を見る
Three new butanolides, 2-(1-methoxy-11-dodecenyl)-penta-2,4-dien-4-olide (1), (2Z, 3S, 4S)-2-(11-dodecenylidene)-3-hydroxy-4-methylbutanolide (2) and (2E, 3R, 4R)-2-(11-dodecenylidene)-3-hydroxy-4-methoxy-4-methyl-butanolide (3), were isolated from the stems of Lindera obtusiloba BLUME. Their chemical structures were assigned by spectroscopic evidence. They exhibited cytotoxicity against cultured human tumor cell lines with their ED_<50> values ranging from 3.19 to 14.63 μg/ml.
- 公益社団法人日本薬学会の論文
- 2000-05-01
著者
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Choi Sang
Research Institute Of Chemical Technology
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Choi Sang
Korea Res. Inst. Of Chemical Technol. Daejeon Kor
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Choi Sang
Korea Research Institute Of Chemical Technology
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Lee Kang
Natural Products Lab. Coll. Of Pharmacy Sungkyunkwan Univ.
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Baek N
Kyung Hee Univ. Suwon Kor
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Lee Kang
Natural Products Laboratory College Of Pharmacy Sung Kyun Kwan University
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Kwon Hak
Natural Products Laboratory College Of Pharmacy Sung Kyun Kwan University
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LEE Kang
College of Pharmacy, Sungkyunkwan University
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Kim H
Neitmtoxicology Program. Department Of Pharmacy Kangwon National University
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Lee Kang
College Of Pharmacy Sungkyunkwan University
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BAEK Nam
Lab. of Natural Products Chemistriy, College of Industry, Kyung Hee University
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Kwon Hak
Graduate School Of East-west Medical Science Kyung Hee University
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Baek Nam
Lab. Of Natural Products Chemistriy College Of Industry Kyung Hee University
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Choi Sang
Korea Food Res. Inst.
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Kwon Hak
Natural Medicine Center, Korea Institute of Science and Technology (KIST), Gangneung
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