Cytotoxic Steroids from the Trunk of <I>Berberis koreana</I>
スポンサーリンク
概要
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A new steroid, itesmol 3-<I>O</I>-palmitate (<B>1</B>), along with two known steroids were isolated from the trunk of <I>Berberis koreana.</I> The structure of <B>1</B> was determined on the basis of spectroscopic analyses involving 2D NMR and chemical reactions. Compound <B>1</B> exhibited potential antiproliferative activity against A549, SK-OV-3, SK-MEL-2, and HCT-15 cell lines (respective IC<SUB>50</SUB> values of 7.41, 9.20, 4.53, and 12.91 μM).
著者
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Lee Kang
Natural Products Lab. Coll. Of Pharmacy Sungkyunkwan Univ.
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Kim Ki
Natural Products Lab. School Of Pharmacy Sungkyunkwan Univ.
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Choi Sang
Korea Food Res. Inst.
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KIM Chung
Natural Products Laboratory, School of Pharmacy, Sungkyunkwan University
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Kim Chung
Natural Products Laboratory School Of Pharmacy Sungkyunkwan University
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