Three New Megastigmane Glucopyranosides from the Cardamine komarovii
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概要
- 論文の詳細を見る
Three new megastigmane glucopyranosides, komaroveside A [(3S,4R,5Z,7E)-3,4-dihydroxy-5,7-megastigmadien-9-one-3-O-β-D-glucopyranoside] (1), komaroveside B [(3S,4S,5S,6R,7E)-5,6-epoxy-3,4-dihydroxy-7-megastigmen-9-one-3-O-β-D-glucopyranoside] (2) and komaroveside C [(3S,4S,5S,6R,7E,9S)-5,6-epoxy-3,4,9-trihydroxy-7-megastigmen-3-O-β-D-glucopyranoside] (3) were isolated, together with eight known compounds, from Cardamine komarovii. The identification of these compounds and the elucidation of their structures were based on 1D- and 2D-NMR spectral data analysis. The isolated compounds were tested for their cytotoxicity against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, HCT15) in vitro using the sulforhodamine B bioassay.
著者
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Lee Kang
Natural Products Lab. Coll. Of Pharmacy Sungkyunkwan Univ.
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Kim Ki
Natural Products Lab. School Of Pharmacy Sungkyunkwan Univ.
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Choi Sang
Korea Food Res. Inst.
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Lee Il
Natural Products Laboratory, School of Pharmacy, Sungkyunkwan University
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Lee Seung
Natural Products Laboratory, School of Pharmacy, Sungkyunkwan University
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