Blood Pressure-lowering Effect of Extract from Lactobacillus casei in Spontaneously Hypertensive Rats (SHR)(Microbiology & Fermentation Industry)
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概要
- 論文の詳細を見る
The effects of oral administration of hot water extract from autologous lysate of Lactobacillm casei (LEx) on the systolic blood pressure (SBP) were studied in spontaneously hypertensive rats (SHR). Oral doses of 10mg/kg of LEx produced a significant decrease of the SBP of SHR, but LEx had no effect in normotensive rats. The long-term administration of LEx (1 or 10mg/kg/day) to SHR from 5 to 17 weeks after birth suppressed the development of hypertension. LEx dialysed against distilled water was separated into a polysaccharide fraction (SG-1), a protein fraction (PR-1), and a nucleic acid fraction (NA-1), and SBP-lowering effects of these materials were investigated in SHR at the same dose (10mg/kg). The most effective material of these three was SG-1.
- 社団法人日本農芸化学会の論文
- 1990-09-23
著者
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Yokokura T
Yakult Central Inst. Microbiological Res. Tokyo Jpn
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Yokokura Teruo
Yakult Central Institute For Microbiological Research
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Yokokura Teruo
Yakult Institute For Microbiological Research
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Yokokura Teruo
Yakult Cent. Inst. Miorobiol.
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WATANUKI Masaaki
Yakult Central Institute for Microbiological Research
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SAWADA Haruji
Yakult Central Institute for Microbiological Research
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FURUSHIRO Masayoshi
Yakult Central Institute for Microbiological Research
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Hirai Koichi
Yakult Institute For Microbiological Research
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SANSAWA Hiroshi
Yakult Central Institute for Microbiological Research
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Sansawa H
Yakult Inst. Microbiological Res. Tokyo Jpn
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Hirai Kouichi
Faculty Of Engineering Science And Research Center For Extreme Materials Osaka University
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MOTOIKE Mahoko
Yakult Institute for Microbiological Research
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HIRAI Kouichi
Yakult Institute for Microbiological Research
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KOBAYASHI Seizaburo
Yakult Institute for Microbiological Research
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Watanuki Masaaki
Yakult Institute For Microbiological Research
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Furushiro M
Yakult Central Inst. Microbiological Res. Tokyo Jpn
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SANSAWA Hiroshi
Yakult Central Institute for MicrobiologicaI Research
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