Effect of Kluyveromyces marxianus YIT 8292 Crude Cell Wall Fraction on Serum Lipids in Normocholesterolemic and Mildly Hypercholesterolemic Subjects
スポンサーリンク
概要
- 論文の詳細を見る
The hypocholesterolemic effects of Kluyveromyces marxianus YIT 8292 crude cell wall (KM-CW) were examined. In pilot studies, KM-CW tablets were administered to mildly hypercholesterolemic subjects at doses of 8.0, 4.0, 2.0, or 1.0 g/d for 4 weeks. Total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) decreased at doses above 2.0 and 4.0 g/d, respectively. Further, we examined the effect of intake of yogurt containing 3.0 or 4.0 g of KM-CW/d for 8 weeks in normal and hypercholesterolemic subjects in a double-blind placebo-controlled study. The intake of either of the KM-CW-containing yogurts was associated with significantly improved TC and LDL-C in hypercholesterolemic subjects, but had no effect on these levels in normal subjects. TC was significantly lower at week 8 in the hypercholesterolemic subjects who ingested yogurt containing 3.0 or 4.0 g of KM-CW than in those who consumed placebo yogurt. Intake of KM-CW might contribute to the prevention of hypercholesterolemia.
- 社団法人 日本農芸化学会の論文
- 2007-04-23
著者
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Ito Masahiko
Yakult Central Inst. For Microbiological Res.
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Yoshida Yuki
Showa Pharmaceutical University
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SAWADA Haruji
Yakult Central Institute for Microbiological Research
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Sawada H
Yakult Central Inst. For Microbiological Res.
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Yoshida Y
Yakult Central Inst. For Microbiological Res.
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Sansawa H
Yakult Inst. Microbiological Res. Tokyo Jpn
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OHISHI Kenji
Yakult Central Institute for Microbiological Research
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YOSHIDA Yasuto
Yakult Central Institute for Microbiological Research
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OKUMURA Takekazu
Yakult Central Institute for Microbiological Research
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SATO Tadashi
Yakult Central Institute for Microbiological Research
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NAITO Eiichiro
Yakult Central Institute for Microbiological Research
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Ohishi K
Yakult Honsha European Research Center For Microbiology Esv
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