Preventive Effect of Streptococcus thermophilus YIT 2001 on Dextran Sulfate Sodium-Induced Colitis in Mice
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概要
- 論文の詳細を見る
We investigated the preventive effect of Streptococcus thermophilus YIT 2001, a lactic acid bacterum having high antioxidative activity, on acute colitis induced by 2.5% dextran sulfate sodium in mice, and compared the effect with that of S. thermophilus YIT 2084 which has lower antioxidative activity. Feeding S. thermophilus YIT 2001 decreased the disease activity index and level of lipid peroxide (the thiobarbituric acid reactive substance content) in the colonic mucosa. The hematocrit and hemoglobin concentrations in the blood of S. thermophilus YIT 2001-fed mice were higher than those of the control mice. S. thermophilus YIT 2084 had no significant effect on these parameters. The results suggest that the antioxidative activity of S. thermophilus YIT 2001 was involved in the improving effect on colitis.
- 社団法人 日本農芸化学会の論文
- 2008-10-23
著者
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Ito Masahiko
Yakult Central Inst. For Microbiological Res.
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Yoshida Yuki
Showa Pharmaceutical University
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SAWADA Haruji
Yakult Central Institute for Microbiological Research
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Sawada H
Yakult Central Inst. For Microbiological Res.
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Yoshida Y
Yakult Central Inst. For Microbiological Res.
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Sansawa H
Yakult Inst. Microbiological Res. Tokyo Jpn
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OHISHI Kenji
Yakult Central Institute for Microbiological Research
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YOSHIDA Yasuto
Yakult Central Institute for Microbiological Research
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OKUMURA Takekazu
Yakult Central Institute for Microbiological Research
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SATO Tadashi
Yakult Central Institute for Microbiological Research
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YOKOI Wakae
Yakult Central Institute for Microbiological Research
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Ohishi K
Yakult Honsha European Research Center For Microbiology Esv
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