Characterization of L-Arabinose-induced Bulge Formation in Escherichia coli IFO 3545 Using L-Arabinose-negative Mutants(Microbiology & Fermentation Industry)

概要

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L-Arabinose-induced bulge formation in Escherichia coli IFO 3545 was observed in L-ribulose-5-phosphate (L-Ru5P) 4-epimerase deficient mutants such as ara-207 and ara-208 as well as the wild type in hypertonic medium with 5% sodium chloride but not in the other L-arabinose-negative mutants. Unlike the case with wild type strain, bulge formation of ara-207 and ara-208 could be induced with 1% L-arabinose without sodium chloride. These results indicated that L-arabinose must be metabolized to L-Ru5P for induction cells and the presence of 5% sodium chloride was thought to regulate the activity of L-Ru5P 4-epimerase to cause accumulation of L-Ru5P as an effector molecule for bulge formation. Also, L-arabinose-induced morphological change was suggested to proceed via a mechanism similar to penicillin-induced inhibition of peptidoglycan metabolism.
社団法人日本農芸化学会の論文
1988-08-23