Metabolism of Drugs. XLV. Synthesis of 2-Naphthyl β-D-Glucofuranosiduronic Acid.
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概要
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1. 2-Naphthyl β-D-grucofuranoside was synthesized from 2-naphthyl diacetyl-β-D-glucofuranosiduronolactone with lithium aluminum hydride, and the ring structure of this compound was examined by periodate oxidation. 2. Catalytic oxidation of 2-naphthyl β-D-glucofuranoside with gaseous oxygen and platinum black yielded 2-naphthyl β-D-glucofuranosiduronic acid. The ring structure of this compound was examined by periodate oxidation. Methyl 2-naphthyl β-D-glucofuranosiduronate was easily converted to 2-naphthyl β-D-glucofuranosiduronolactone. Methylation and acetylation of 2-naphthyl β-D-glucofuranosiduronic acid yielded 2-naphthyl diacetyl-β-D-glucofuranosiduronolactone.
- 社団法人日本薬学会の論文
- 1964-06-25
著者
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吉田 和夫
Daiichi College Of Pharmaceutical Sciences
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加藤 敬太郎
九州大学薬学部
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塚元 久雄
Institute of Pharmaceutical Sciences, Faculty of Medicine, Kyushu University
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加藤 敬太郎
Institute of Pharmaceutical Sciences, Faculty of Medicine, Kyushu University
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吉田 和夫
Institute of Pharmaceutical Sciences, Faculty of Medicine, Kyushu University
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Kato Keitaro
Division Of Physiological Chemistry Faculty Of Pharmaceutical Sciences Kyushu University
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塚元 久雄
Institute Of Pharmaceutical Sciences Faculty Of Medicine Kyushu University
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