光学活性化合物に魅せられた50年 : 山田俊一先生にきく

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概要

• 論文の詳細を見る
• 社団法人日本薬学会の論文
• 1994-11-01

著者

• 山田 俊一

  東京大学

• 山田 俊一

  東京大学薬学部

• 寺島 孜郎

  (財)相模中央化学研究所

• 寺島 孜郎

  Faculty Of Pharmaceutical Sciences University Of Tokyo:(present Address)sagami Chemical Research Cen

関連論文

• 立体化学の研究(第33報)L-Proline誘導体を用いたEnamineの不斉誘起反応による不斉合成(-)-Bisdehydroestrone Methyl Etherの不斉合成
• 立体化学の研究(第32報)L-Proline誘導体を用いたEnamineの不斉誘起反応による不斉合成, ステロイドならびにテルペン合成中間体の不斉合成
• Stereochemical Studies. XXIX. Asymmetric Synthesis of 2-Alkylcyclohexanones via optically Active Lithioenamines
• Stereochemical Studies. VII. Thermal Rearrangement of α-Hydroxyimines to α-Aminoketones using optically Active Open Chain Compounds
• Studies on optically Active Amino Acids. XVIII. Studies on α-Methyl-α-amino Acids. XIV. Several Optical Properties of α-Methyl-α-amino Acids
• Studies on Optically Active Amino Acids. XIV. Studies on α-Alkyl-α-amino acids. VII. Determination of Absolute Configuration of Optically Active α-Methylphenylglycine Configuration of Optically Active α-Methylphenylglycine and 1-Methyl-1-phenylpropylamine
• 日本薬学会学術賞受賞 古賀憲司氏の業績
• 名誉会員管澤重彦先生を偲びて
• オクテット
• オクテット
• 光学活性化合物に魅せられた50年 : 山田俊一先生にきく
• Stereochemical Studies. LX. Neighboring Phenyl Group Participation. I. Stereospecific Transformation of L-Phenylalanine to Optically Active Tropic Acid
• Pyrimidine Derivatives. V. Structure-Activity Studies of Antihypertensive Quinazoline Derivatives Using the Adaptive Least-Squares Method
• Pyrimidine Derivatives. VII. Structure-Activity Relationship of Hypoglycemic 4-Amino-2-(1-piperazinyl) pyrimidines investigated by the Adaptive Least-Squares Method
• Pyrimidine Derivatives. VI. Synthesis of 2-(1-Piperazinyl)-5,6-polymethylenepyrimidine Derivatives and Determination of Their Hypoglycemic Activity
• Stereochemical Studies. LIX. Asymmetric Transamination from (S)-α-Amino Acids. Synthesis of optically Active Amines by Chemical Transamination of (S)-α-Amino Acid Esters to Ketones
• SYNTHESIS OF L-TRYPTOPHAN FROM L-GLUTAMIC ACID
• Pyrimidine Derivatives. II. New Synthesis and Reactions of 4-Amino-2-methylthiopyrimidine Derivatives
• Amino Acids and Peptides. XXXI. Phosphorus in Organic Synthesis. XVIII. Synthesis of Porcine Motilin by the Solid-phase Method using Diphenyl Phosphorazidate (DPPA) and Diethyl Phosphorocyanidate (DEPC)
• Amino Acids and Peptides. XXX. Phosphorus in Organic Synthesis. XVII. Application of Diphenyl Phosphorazidate (DPPA) and Diethyl Phosphorocyanidate (DEPC) to Solid-phase Peptide Synthesis
• 立体化学の研究(第56報)(Acetylacetonato)[(1R, 2S)-N-alkylephedrinato]-dioxomolybdenumを不斉触媒とするアリルアルコールの不斉エポキシ化反応
• 立体化学の研究(第55報)不斉エポキシ化触媒としてのモリブデン錯体の合成
• イソプロパノール溶媒中における水素化ホウ素ナトリウムによるカルボジイミド類よりホルムアミジン類の合成反応
• Stereoselective Reactions. II. Asymmetric Synthesis of β-Substituted Aldehydes by Michael Reaction using Chiral α, β-Unsaturated Aldimines
• Stereoselective Reactions. I. A highly Efficient Asymmetric Synthesis of β-Substituted Aldehydes via 1,4-Addition of Grignard Reagents to optically Active α, β-Unsaturated Aldimines
• Stereochemical Studies. LIV. A Biogenetic-type Asymmetric Synthesis of optically Active Galanthamine from L-Tyrosine
• Stereochemical Studies. LIII. An Asymmetric Synthesis of (3S 15S 20R)-Yohimbone from L-Tryptophan by 1,3-Transfer of Asymmetry
• 36 メソ型化合物を用いる光学活性プロスタグランディン,ステロイド中間体の新合成法
• Synthesis of Formamidines from Carbodiimides with Sodium Borohydride in Isopropanol
• Amino Acids and Peptides. XXIX. A New Efficient Asymmetric Synthesis of α-Amino Acid Derivatives with Recycle of a Chiral Reagent-Asymmetric Alkylation of a Chiral Schiff Base from Glycine
• Studies on the Synthesis of 4-[1,8-Dioxygenated-9,10-dioxoanthracen (or anthracen)-2-yl] butanoic Acid Derivatives
• Stereochemical Studies. XXIII. Stereochemistry of the Thermal Isocyanide-Cyanide Rearrangement
• 効率的合成法の開発に感動と興奮を求めて
• 生物活性物質の効率的合成法の開発とその創薬化学への展開
• Stereochemical Studies. XLVII. Asymmetric Reduction of 2-Alkyl-1,3,4-cyclopentanetriones with Lithium Aluminum Hydride decomposed by optically Active β-Aminoalcohols. Syntheses of optically Active Allethrolone and Prostaglandin E_1
• Stereochemical Studies. XLV. A Novel Regiospecific Ring Opening of optically Active 2-Substituted-1-tosylaziridines
• Stereochemical Studies. XLVI. Studies on the Synthesis of 4-Acetoxy-cyclopentane-1,3-dione Derivatives
• Stereochemical Studies. XLIV. Exploitation of the New Synthetic Scheme for Chiral Additives Usable in Asymmetric Syntheses. Novel Syntheses of optically Active γ-Amino Acids and Pyrrolidines from L-α-Amino Acids
• Stereochemical Studies. XLIII. Novel Reactivity of Organometallic Reagents to 5,5-Ethylenedioxy-2-methyl-2-phenylcyclohexanone
• Stereochemical Studies. XLII. Asymmetric Synthesis of naturally Occurring Podocarpic Acid
• Stereochemical Studies. XLI. Asymmetric Synthesis of optically Active 4a-Methyl-4,4a, 9,10-tetrahydro-2 (3H)-phenanthrone Derivatives, Key Intermediates for Total Syntheses of optically Active Diterpenes and Steroids
• Stereochemical Studies. XL. A Biomimetic Conversion of L-Lysine into optically Active 2-Substituted Piperidines. Syntheses of D- and L-Pipecolic Acid, and (S) (+)-Coniine from L-Lysine
• Stereochemical Studies. XXXIX. A Novel Method for the Preparation of Optically Active Aldehydes. Syntheses of Optically Active (R) (+)-α-Cyclocitral, (S) (+)-Dehydrovomifoliol, and (S) (+)-Abscisic Acid
• Stereochemical Studies. XXXV. A Biogenetic-type Asymmetric Cyclization. Syntheses of optically Active α-Cyclocitral and trans-α-Damascone
• Stereochemical Studies. XXXIV. A Novel Biogenetic-type Cyclization of Citral to α-Cyclocitral via an Enamine
• プロスタグランディンの化学合成 (プロスタグランディン)
• 2 光学活性テルペン類の不斉合成 : α-cyclocitralの不斉合成を中心として
• Stereochemical Studies. XXII. Thermal Rearrangement of S(-)-1-Phenylethyl Isocyanide
• Amino Acids and Peptides. I. Novel Peptide Bond Formation Catalyzed by Metal Ions. I. Formation of Glycine Peptide Esters
• 18 不斉合成による(+)-Mesembrineの合成
• 光学活性な生物活性化合物の合成を目指して
• Chemistry of Amino Acids. VI. Studies on α-Alkyl-α-amino Acids. X. Unusual Alkyl Migration in the Hofmann Degradation of 5-(2-Dialkylaminoethyl)-5-methylhydantoin Quarternary Ammonium Hydroxide Anhydronium Base
• Studies on Optically Active Amino Acids. XV. Studies on α-Alkyl-α-amino Acids. VIII. Absolute Configuration of Optically Active α-Methylserine and 2-Amino-2-methyl-3-butenoic Acid.
• Stereochemical Studies. XXI. Studies on α-Alkyl-α-amino Acids. XV. Application of Thermal Isocyanide-Cyanide Rearrangement to R-S Conversion of α-Methylphenylalanine
• Amino Acids and Peptides. VI. Novel Peptide Bond Formation catalyzed by Metal Ions. IV. Formation of optically Active Amino Acid Amides and Peptide Amides
• Stereochemical Studies. VI. Steric Course of Intramolecular Alkylations using optically Active Amine Derivatives
• 薬学における有機合成の現状と将来
• Novel Ethynylcerium(III) Reagents as Efficient Tools for Constructing the α-Hydroxy Methyl Ketone Moiety of Anthracyclinones
• Elucidation of the Racemization Mechanism of the α-Hydroxy Ketone Moiety (C_9-Position) of Optically Active Anthracyclinone Derivatives
• Novel Synthesis of Optically Pure Anthracyclinone Intermediates by the Use of Microbial Asymmetric Reduction with Fermenting Baker's Yeast
• Asymmetric Reduction of Various Types of Ketones with Lithium Aluminum Hydride partially decomposed with (-)-N-Methylephedrine and N-Ethylaniline
• Asymmetric Synthesis of optically Active Anthracyclinone Intermediate and 4-Demethoxyanthracyclinones by the Use of a Novel Chiral Reducing Agent
• Development of a Novel Synthetic Route to optically Active Anthracyclinones : Preliminary Synthesis of the Racemic Key Intermediate
• 30 光学活性アンスラサイクリノンの不斉合成
• Asymmetric Halolactonization Reactions. 3. Asymmetric Synthesis of optically Active Anthracyclinones
• Synthesis of Enantiomeric Pairs of Vicinal-Diols from L-α-Amino Acids by the Use of Organolithium Reagents : Its Application to optically Active Epoxyterpene Synthesis
• Synthesis of optically Active α-Alkyl or α-Aryl Acids from L-α-Amino Acids by the Use of Organocopper Reagents
• 水素化ホウ素ナトリウムによる最近の興味ある還元反応
• 日本薬学会奨励賞受賞 大塚雅巳氏の業績
• Stereochemical Studies. V. Intramolecular C-H Bond Insertion Reaction of Acyl Nitrene generated from optically Active Acyl Azide
• Stereochemical Studies. IV. Studies on α-Alkyl-α-amino Acids. XII. Hofmann and Curtius Rearrangements of S (+)-2-Cyano-2-methyl-3-phenylpropionic Acid
• Stereochemical Studies. III. Chemical Correlation of Absolute Configuration of 2-Cyano-2-methyl-3-phenylpropionic Acid to α-Methyl-α-isopropylsuccinic Acid
• Studies on Optically Active Amino Acids. XVI. Studies on α-Alkyl-α-amino Acids. XI. Synthesis of R-α-Methylphenylalanine from S (+)-2-Methyl-3-phenylpropionic Acid by the Direct Conversion of the optically Active C-H Bond into the C-N Bond
• Stereochemical Studies. II. Thermal and Photochemical Decompositions of Optically Active Alkyl Azidoformates
• 光学活性アミノ酸を用いる天然光学活性化合物の合成 (新しい有機合成反応--その発想と展開)

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