Stereochemical Studies. LX. Neighboring Phenyl Group Participation. I. Stereospecific Transformation of L-Phenylalanine to Optically Active Tropic Acid
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概要
- 論文の詳細を見る
Trifluoroacetolysis of (S)-3-phenyllactic acid ester sulfonate ((S)-7), obtained from L-phenylalanine via nitrous acid deamination followed by ethanolysis, afforded (R)-tropic acid ester ((R)-8) in good yield by phenyl migration with inversion, while acetolysis followed by ethanolysis afforded (R)-phenyllactic acid ester ((R)-6b) in good yield by substitution with inversion. Mechanistic aspects of these reactions are discussed.
- 社団法人日本薬学会の論文
- 1984-11-25
著者
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山田 俊一
東京大学
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荘 祚敏
Institute of Applied Chemistry, National Chiao-Tung University
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山田 俊一
Republic of China and Faculty of Pharmaceutical Sciences, Josai University
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荘 祚敏
Institute Of Applied Chemistry National Chiao-tung University
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