COMPARATIVE UPTAKE OF CIMETIDINE BY RAT CHOROID PLEXUS BETWEEN THE LATERAL AND THE 4TH VENTRICLES
スポンサーリンク
概要
- 論文の詳細を見る
It is suggested that cimetidine interacts with the transport system for organic anions and oligopeptides in the rat lateral ventricular choroid plexus. In this study, we studied the transport system of cimetidine in the rat 4th ventricular choroid plexus to examine the heterogeneity in the ability to accumulate cimetidine between the lateral and the 4th ventricular choroid plexus. The similar time course of the accumulation of cimetidine was obtained between both choroid plexuses. Furthermore, the accumulation of cimetidine by the choroid plexus from the 4th ventricle was inhibited by unlabelled cimetidine (1 mM) and benzylpenicillin (1 mM) but not by tetraethyammonium (1 mM). These findings suggested that the rat choroid plexuses from the lateral and the 4th ventricle have similar characteristics in transporting cimetidine.
- 社団法人日本薬学会の論文
著者
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Suzuki Hiroshi
Faculty of Science, Kyoto University
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Sawada Y
Univ. Tokyo Tokyo Jpn
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Sawada Yasufumi
Faculty Of Pharmaceutical Sciences Tokushima Bunri University:faculty Of Pharmaceutical Sciences Uni
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HANANO Manabu
Faculty of Pharmaceutical Sciences, University of Tokyo
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SUGIYAMA Yuichi
Faculty of Pharmaceutical Sciences, University of Tokyo
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IGA Tatsuji
Faculty of Pharmaceutical Sciences, University of Tokyo
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IGA Tatsuji
International University of Health and Welfare
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Hanano Manabu
Faculty Of Pharmaceutical Sciences University Of Tokyo
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Hanano M
Department Of Pharmaceutics College Of Pharmacy Nihon University
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Hanano M
Department Of Pharmaceutical Science College Of Pharmacy Nihon University
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Hanano Manabu
Faculty Of Pharmaceutical Science University Of Tokyo
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Sugiyama Yuichi
Faculty Of Pharmaceutical Sciences University Of Tokyo
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Iga T
Department Of Pharmacy University Of Tokyo Hospital
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Iga Tatsuji
Department Of Biopharmaceutics Faculty Of Pharmaceutical Sciences Nagoya City University:department
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Iga Tatsuji
Faculty Of Pharmaceutical Sciences University Of Tokyo
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Hanano M
Faculty Of Pharmaceutical Sciences University Of Tokyo
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Hanano Manabu
Department Of Biopharmaceutics Faculty Of Pharmaceutical Sciences Nagoya City University:department
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Sato Hiroaki
Fac. Of Pharm. Sci. Univ. Of Tokyo
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Iga T
Department Of Biopharmaceutics Faculty Of Pharmaceutical Sciences Nagoya City University:department
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Iga Tatsuji
Department Of Pharmacy Faculty Of Pharmaceutical Sciences University Of Tokyo
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Sugiyama Yuichi
Faculty Of Pharmaceutical Sciences The University Of Tokyo
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Iga Tatsuji
Division Of Gastroenterology Department Of Medicine Kurume University School Of Medicine
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IGA TATSUJI
Department of Pharmaceutics, University of Tokyo Hospital, University of Tokyo
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