Analyses of Rabbit Platelet Proteo-Chondroitin Sulfates Localized on the Surface and in the Granules
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概要
- 論文の詳細を見る
Platelet proteo-chondroitin sulfates localize on the surface and in the granules. Western blotting method is able to selectively detect core-proteins prepared from proteo-chondroitin sulfates by chondroitinase ABC digestion. A very highly sensitive high-performance liquid chromatographic method was established for the determination of chondroitin sulfates as their unsaturated disaccharides. These methods were applied to rabbit platelet proteo-chondroitin sulfates. It was found that both rabbit platelet surface proteo-chondroitin sulfate and granule proteo-chondroitin sulfate consist of a predominantly homogeneous chondroitin 4-sulfate and a single core-protein having a molecular weight of approximately 26 kDa.
- 公益社団法人日本薬学会の論文
著者
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IMANARI Toshio
Faculty of Pharmaceutical Sciences, Chiba University
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Takayama Hiromitsu
Laboratory Of Molecular Structure And Biological Function Graduate School Of Pharmaceutical Sciences
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Akiyama H
Chiba Univ. Chiba Jpn
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Imanari^ Toshio
Faculty Of Pharmaceutical Sciences Chiba University
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Imanari Toshio
Faculty Of Pharmaceutical Sciences Chiba University
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Toyoda Hidenao
Faculty Of Pharmaceutical Sciences Chiba University
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Koshiishi I
Faculty Of Pharmaceutical Sciences Chiba University
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Koshiishi Ichiro
Faculty Of Pharmaceutical Sciences Chiba University
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Ikei Tatsuo
Faculty Of Pharmaceutical Sciences Chiba University
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Oguma Toshihiro
Drug Metabolism And Analytical Chemistry Research Laboratory Daiichi Pharmaceutical Co. Ltd.
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OGUMA Toshihiro
Faculty of Pharmaceutical Sciences, Chiba University
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AKIYAMA Hiroshi
Faculty of Pharmaceutical Sciences, Chiba University
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Akiyama Hiroshi
Faculty Of Pharmaceutical Sciences Chiba University
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Imanari T
Faculty Of Pharmaceutical Sciences Chiba University
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