A New Gluco Indole Alkaloid, 3,4-Dehydro-5-carboxystrictosidine, from Preruvian Una de Gato (Uncaria tomentosa)
スポンサーリンク
概要
- 論文の詳細を見る
A new gluco indole alkaloid, 3,4-dehydro-5-carboxystrictosidine, was obtained from Peruvian Una de Gato(Cat's Claw, original plant : Uncaria tomentosa) together with two known gluco indole alkaloids. This compound was the first example of isolation of a gluco monoterpenoid indole alkaloid having a 3,4-dihydro-β-carboline ring system from nature. A characteristc feature of the compound was the quick replacement of the methylene hydrogens on C-14 with deuterium that was observed when it was dissolved in CD_3OD. We demonstrated a similar proton-deuterium exchange on a model compound, 1-methyl-3,4-dihydro-β-carboline, in CD_3OD solution.
- 社団法人日本薬学会の論文
- 2000-10-01
著者
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Takayama Hiroaki
帝京大学 薬
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高山 廣光
Graduate School Of Pharmaceutical Sciences Chiba Univ.
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HASHIMOTO Ken-ichiro
Graduate School of Pharmaceutical Sciences, Chiba University
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Yamazaki Mami
Department Of Molecular Biology And Biotechnology Graduate School Of Pharmaceutical Sciences Chiba U
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Yokota M
School Of Pharmaceutical Sciences Showa University
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Shirakawa Seiichiro
Faculty Of Pharmaceutical Sciences Chiba University
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KITAJIMA Mariko
Faculty of Pharmaceutical Sciences, Chiba University
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TAKAYAMA Hiromitsu
Faculty of Pharmaceutical Sciences, Chiba University
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AIMI Norio
Faculty of Pharmaceutical Sciences, Chiba University
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HASHIMOTO Ken-ichiro
Faculty of Pharmaceutical Sciences, Chiba University
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YOKOYA Masashi
Faculty of Pharmaceutical Sciences, Chiba University
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SAKAI Shin-ichiro
Faculty of Pharmaceutical Sciences, Chiba University
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Takayama Hiromitsu
Laboratory Of Molecular Structure And Biological Function Graduate School Of Pharmaceutical Sciences
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Aimi N
Graduate School Of Pharmaceutical Sciences Chiba University
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Aimi Norio
Faculty Of Pharmaceutical Sciences Chiba University
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Yokoya M
Chiba Univ. Chiba Jpn
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Hashimoto K
Graduate School Of Pharmaceutical Sciences Chiba University
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Takayama Hiromitsu
Faculty Of Pharmaceutical Sciences Chiba University
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Kitajima Mariko
Faculty Of Pharmaceutical Sciences Chiba University
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Sakai Shin-ichiro
Faculty Of Pharmaceutical Sciences Chiba University
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Yamazaki Mami
Department Of Molecular Biology And Biotechnology Graduate School Of Pharmaceutical Sciences Chiba U
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Kitajima M
Department Of Biofunctional Molecular Chemistry Graduate School Of Pharmaceutical Sciences Chiba Uni
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