Localization of Ghrelin-Producing Cells in the Stomach of the Rainbow Trout(Oncorhynchus mykiss)(Endocrinology)
スポンサーリンク
概要
- 論文の詳細を見る
Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor (GHS-R), was isolated from the rat stomach and determined to be n-octanoylated 28-amino-acid peptide. In this study, we studied the distribution of ghrelin-producing cells (ghrelin cells) in the gastrointestinal tract of male and female rainbow trout (Oncorhynchus mykiss) by immunohistochemistry using N-terminal region-recognizing antibody and also by in situ hybridization using a trout ghrelin-specific cRNA probe. Ghrelin cells were found in the mucosal layer of the somach but not in the myenteric plexus, and no ghrelin cells were observed in other regions of the gastrointestinal tract. Ghrelin cells could be classified into two types: closed- and opened-type cells. The density of ghrelin cells increased gradually in the direction from the cardiac to pyloric portions of the stomach in both sexes. The number of ghrelin cells per unit area seemed to be higher in females that in males. In conclusion, trout gharelin cells exist in the stomach and are classified itno two types of cells, closed- and opened-type cells.
- 社団法人日本動物学会の論文
- 2004-01-25
著者
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Kaiya Hiroyuki
Department of Biochemistry, National Cardiovascular Center Research Institute
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Kangawa Kenji
Department of Biochemistry, National Cardiovascular Center Research Institute
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SAKAI Takafumi
Department of Regulation-Biology, Faculty of Science, Saitama University
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YAMAZAKI Mami
Department of Oral Pathology, School of Dentistry, Health Sciences University of Hokkaido
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毛利 孝之
九州大学大学院動物学研究室
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毛利 孝之
九州大学 農研究院
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INOUE Kinji
Department of Regulation Biology, Faculty of Science, Saitama University
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Yamazaki M
Laboratory Of Cell Biology Department Of Regulation Biology Faculty Of Science Saitama University
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Yamazaki Mami
Department Of Molecular Biology And Biotechnology Graduate School Of Pharmaceutical Sciences Chiba U
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Kobayashi Hisae
埼玉大学 理学部
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Sakata Ichiro
Area Of Regulatory Biology Division Of Life Science Graduate School Of Science And Engineering Saita
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Sakata Ichiro
Department Of Regulation Biology Faculty Of Science Saitama University
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Kangawa K
Research Institute National Cardiovascular Center
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Kangawa Kenji
Department Of Biochemistry National Cardiovascular Center Research Institute
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Mori Takayuki
Department Of Zoology Graduate School Of Agriculture Kyusyu University
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Kaiya Hiroyuki
National Cardiovascular Center Res. Inst. Jpn
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Kaiya H
National Cardiovascular Center Res. Inst. Osaka Jpn
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Kaiya Hiroyuki
Department Of Biochemistry National Cardiovascular Center Research Institute
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Kawauchi H
Kitasato Univ. Ofunato Jpn
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Yamazaki Miho
Faculty Of Agriculture And Life Science Hirosaki University
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Mori Tsukasa
Department of Marine Science and Resources College of Bioresource Sciences, Nihon University
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Sakai Takehiko
Institute Of Biological Sciences University Of Tsukuba
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Inoue Kinji
Department Of Cell Biology Faculty Of Science Saitama University
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Mori Tsukasa
Laboratory Of Marine Molecular Biochemistry College Of Bioresource Sciences Nihon University
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Mohri T
Department Of Zoology Graduate School Of Agriculture Kyushu University
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毛利 孝之
九州大学大学院農学研究院生物資源開発管理学
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Mohri Takayuki
Department Of Zoology Faculty Of Agriculture Kyushu University
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Sakai Takafumi
Department Of Cell Biology Faculty Of Science Saitama University
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毛利 孝之
Faculty Of Agriculture Kyushu University
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Sakata Ichiro
Area Of Regulatory Biology Division Of Life Science Graduate School Of Science And Engineering Saita
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Sakai Takafumi
Area Of Regulatory Biology Division Of Life Science Graduate School Of Science And Engineering Saita
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毛利 孝之
信州大学教育学部学生
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SAKAI Takafumi
Department of Applied Microbial Technology, The Kumamoto Institute of Technology
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