Characterization and Determination of Human Urinary Keratan Sulfate
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概要
- 論文の詳細を見る
Keratan sulfate was isolated from normal human urine was characterized by sugar compositional analysis and ^1H-NMR spectroscopy. It was found that KS from human urine is classified as skeletal type (KS-II type chain) with an O-glycosidic linkage between galatosamine and serine (or theronine). ^1H-NMR studies revealed that urinary KS is not a proteoglycan but a polysaccharide (molecular weight is about 5kDa). The quantitation of human urinary KS by HPLC showed that urinary KS is excreted at constant levels (0.07±0.015 μg/mg creatinine).
- 公益社団法人日本薬学会の論文
- 1998-01-15
著者
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IMANARI Toshio
Faculty of Pharmaceutical Sciences, Chiba University
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Toida Toshihiko
Graduate School of Pharmaceutical Sciences, Chiba University
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Takayama Hiromitsu
Laboratory Of Molecular Structure And Biological Function Graduate School Of Pharmaceutical Sciences
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Toida T
Department Ofbioanalytical Chemistry Graduate School Of Pharmaceutical Sciences Chiba University
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Toida Toshihiko
Faculty Of Pharmaceutical Sciences Chiba University
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Imanari^ Toshio
Faculty Of Pharmaceutical Sciences Chiba University
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Imanari Toshio
Faculty Of Pharmaceutical Sciences Chiba University
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Toyoda Hidenao
Faculty Of Pharmaceutical Sciences Chiba University
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Ikei Tatsuo
Faculty Of Pharmaceutical Sciences Chiba University
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DEMACHI Yoshikuni
Faculty of Pharmaceutical Sciences, Chiba University
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KOMORIYA Shizuyo
Faculty of Pharmaceutical Sciences, Chiba University
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FURUYA Nobuyoshi
Faculty of Pharmaceutical Sciences, Chiba University
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Imanari T
Faculty Of Pharmaceutical Sciences Chiba University
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Furuya Nobuyoshi
Faculty Of Pharmaceutical Sciences Chiba University
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Komoriya Shizuyo
Faculty Of Pharmaceutical Sciences Chiba University
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Demachi Y
Faculty Of Pharmaceutical Sciences Chiba University
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