Formic Acid Reduction. XXI. Reductive Cleavage Reaction of p-Dimethylamino-substituted Triphenylmethanes induced by Formate
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概要
- 論文の詳細を見る
On heating with the formate, triethylammonium formate, known as the distillable liquid given by 5HCO_2H・2NEt_3,several triphenylmethanes possessing dimethylamino group on their benzene rings have been shown to suffer reductive cleavage at the carbon bond bound to the dimethylaminophenyl carbon to give N, N-dimethylaniline and diphenylmethanes. The reaction is controlled by the structure and the substituent effect. Isotopic experiments using a deuterated formate has revealed that formyl hydrogen of formic acid is transferred to the methylene carbon of the diphenylmethane product. From the assembled data, a possible mechanism is proposed.
- 社団法人日本薬学会の論文
- 1974-08-25
著者
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関屋 実
School Of Pharmaceutical Sciences University Of Shizuoka
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鈴木 邦夫
School Of Pharmaceutical Sciences University Of Shizuoka
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鈴木 邦夫
Shizuoka College of Pharmacy
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関屋 実
Shizuoka College of Pharmacy
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