Ring Transformation of Fused Pyridazines. III. 1-Substituted Phthalazines with Ynamines

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概要

• 論文の詳細を見る

• In the reaction of 1-substituted phthalazines with ynamines, there are three patterns of ring transformation, giving naphthalene derivatives through addition-cyclization-denitrogenation (type A), giving benzodiazocine derivatives through addition-cyclization-ring expansion (type B), and giving penta-substituted pyridine derivatives through N-N bond cleavage of the pyridazine ring (type C). In these reactions, it is considered that the substituent group at the 1-position of the phthalazine ring is a significant factor determining the outcome.

• 社団法人日本薬学会の論文
• 1995-04-15

著者

• 東野 武郎

  School Of Pharmaceutical Sciences University Of Shizuoka

• 丹治 健一

  School of Pharmaceutical Sciences, University of Shizuoka

• 大石 悦男

  Division Of Environmental Health Sciences Graduate School Of Nutritional & Environmental Science

• 大石 悦男

  Laboratory Of Organic Chemistry Graduate School Of Nutritional And Environmental Sciences University

• 岩本 憲人

  School of Pharmaceutical Sciences, University of Shizuoka

• 鈴木 澄子

  School of Pharmaceutical Sciences, University of Shizuoka

• 宮下 晶

  School of Pharmaceutical Sciences, University of Shizuoka

• 鈴木 澄子

  School Of Pharmaceutical Sciences University Of Shizuoka

• 宮下 晶

  School Of Pharmaceutical Sciences University Of Shizuoka

• 丹治 健一

  School Of Food & Nutritional Sciences University Of Shizuoka

• Suzuki S

  Faculty Of Pharmacy Meiji University

• 岩本 憲人

  静岡県立大学薬学部

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