Mechanisms for Production and Secretion of Hormones in Physiologic and Pathologic Conditions
スポンサーリンク
概要
- 論文の詳細を見る
Many aspects of molecular mechanisms for the production of hormones have been clarified by recent, rapidly growing molecular technologies. The cloning of various transcription factors and the gene targeting technologies have contributed a great deal in studying the essential aspects of hormone production. Prohormone convertases (PCs) and the intracellular secretory mechanisms of the prohormones have been other inevitable issues in the proper function of the hormone secreting cells. In the field of pituitary research, transcription factors such as Pit-1, Ptx1, Prop-1, NeuroD1, GATA2, SF-1, and DAX-1, clarify three cell lineages in the functional development of the individual pituitary cells. In the human pituitary adenomas, occasionally their hormone production is 'aberrant', which causes overlap in the lineages. Molecular mechanisms have been proposed to be resulted from 'aberrant' combinations of the transcription factors by the gene transfection method. Histochemistry and cytochemistry are expected to play essential future roles in the research on the physiological and pathological aspects of hormone production.
- 日本組織細胞化学会の論文
- 2003-11-02
著者
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Takekoshi Susumu
Department of Pathology, Tokai University School of Medicine
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Osamura Robert
Department of Pathology, Tokai University School of Medicine
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Egashira Noboru
Department of Pathology, Tokai University School of Medicine
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Umemura Shinobu
Department of Pathology, Tokai University School of Medicine
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Yasuda Masanori
Department of Pathology, Saitama Medical University International Medical Center
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TERAMOTO Akira
Departments of Neurosurgery, Nippon Medical School
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Osamura R
Department Of Pathology Tokai University School Of Medicine
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Kajiwara Hiroshi
Department of Pathology, Tokai University School of Medicine
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Kumaki Nobue
Department of Pathology, Tokai University School of Medicine
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Osamura R.yoshiyuki
東海大学 医学研究科病理病態学
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Takekoshi Susumu
日本獣医畜産大学 獣医学部獣医外科学教室
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Osamura Yoshiyuki
東海大学 医学研究科病理病態学
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Osamura R.yoshiyuki
東海大学 医学部病理診断学
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Osamura R
東海大学 医学研究科病理病態学
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Osamura R.yoshiyuki
東海大学教育・研究支援センター
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SANNO Naoko
Department of Neurosurgery, Tama-Nagayama Hospital, Nippon Medical School
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Sanno Naoko
日本医科大学 脳神経外科
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Sanno N
Department Of Neurosurgery Nippon Medical School
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Sanno Naoko
Department Of Neurosurgery Nippon Medical Sehool
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Osamura Robert
Dep. Of Pathology Tokai Univ. School Of Medicine
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Katakami H
Miyazaki Medical School Miyazaki Jpn
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Katakami Hideki
宮崎医科大学 内
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Teramoto Akira
Department Of Neurosurgery Nippon Medical School
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Teramoto Akira
流山中央病院 脳神経外科
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Tahara Shigeyuki
Department Of Neurosutgery Nippon Medical School
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Yasuda M
Department Of Pathology Tokai University School Of Medicine
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Yasuda Masanori
Department Of Pathology School Of Medicine Tokai University
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Yamazaki Michio
Department of Neurosurgery, Nippon Medical Sehool
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Miyai Syunsuke
Department of Pathology, Tokai University School of Medicine
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UMEMURA Shinobu
Cytology and Core Needle Biopsy Subcommittee of the Japanese Breast Cancer Society
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Teramoto A
Nippon Medical School Tokyo Jpn
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Yasuda Masanori
Departments Of Pathology Tokai University School Of Medicine
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Katakami Hideki
3rd Department Of Internal Medicine Medical College
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Takekoshi Susumu
Department Of Pathodiagnostics Course Of Basic Clinical Science Tokai University School Of Medicine
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Kajiwara Hiroshi
Department Of Pathology Tokai University School Of Medicine
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Kajiwara Hiroshi
Pharmacological Research Laboratories Drug Safety Testing Center Co. Ltd.
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Osamura R
Tokai Univ. School Of Medicine Kanagawa Jpn
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Kajiwara Hiroshi
Department Pathology Of Tokai University School Of Medicine
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Hoya Katsumi
Department Of Neurosurgery Teikyo University Chiba Medical Center
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Kumaki Nobue
Department Of Pathology Tokai University School Of Medicine
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Osamura Robert
Department Of Pathology School Of Medicine Tokai University
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Miyai Syunsuke
Department Of Pathology Tokai University School Of Medicine
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Miyai Shunsuke
Department Of Pathology Tokai University School Of Medicine
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TERAMOTO Akira
Faculty of Textile Science and Technology, Shinshu University
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Teramoto A
Department Of Neurosurgery Nippon Medical School
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Katakami Hideki
Departments Of Internal Medicine Miyazaki Medical College
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Osamura R.
Tokai Univ. School Of Medicine Kanagawa Jpn
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Umemura S
Department Of Pathology Tokai University School Of Medicine
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Umemura Shinobu
Department Of Pathology & Division Of Diagnostic Pathology Tokai University School Of Medicine
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Kajiwara Hiroshi
Departments Of Pathology School Of Medicine Tokai University
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Yamazaki Michio
Department Of Pathology Saitama Medical University International Medical Center
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Yamazaki Michio
Department Of Neurosurgery Nagareyama Central Hospital
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Sanno Naoko
Department Of Neurosurgery Nippon Medical School
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Sanno N
Department Of Neurosurgery Nippon Medical Sehool
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Katakami H
Department Of Pathology Tokai University School Of Medicine
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Osamura R
Tokai Univ. School Of Medicine
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Mizoguchi Yoshikazu
Department Of Maxillofacial Diagnostic Science Division Of Pathology Kanagawa Dental College
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Marugami Yoshihisa
Department Of Pathology Fujita Health University School Of Medicine
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Yasuda Mitsuhiro
Department Of General Surgery Fukuoka Dental College Hospital
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Teramoto Akira
Department Of Functional Polymer Science Shinshu University
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Osamura R.yoshiyuki
Dept Of Pathology Tokai Univ School Of Medicine
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Umemura S
Tokai Univ. School Of Medicine
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Egashira Noboru
Department Of Pathology Tokai University School Of Medicine
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Kajiwara Hiroshi
Department Of Neurosurgery Teikyo University Chiba Medical Center
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Yasuda Masanori
東海大学 医学部病理学
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Yasuda Masanori
Department Of Pathology Saitama Medical University International Medical Center
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Yasuda Masanori
Department Of Neurosurgery Nippon Medical School
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