Osamura Robert | Dep. Of Pathology Tokai Univ. School Of Medicine
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概要
関連著者
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Osamura Robert
Dep. Of Pathology Tokai Univ. School Of Medicine
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Osamura R.
Department Of Pathology School Of Medicine Tokai University
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OSAMURA R.
Department of Pathology, Tokai University School of Medicine
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Osamura R.yoshiyuki
東海大学 医学研究科病理病態学
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Osamura R.yoshiyuki
東海大学教育･研究支援センター
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Osamura R.yoshiyuki
東海大学 医学部病理診断学
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Osamura R
東海大学 医学研究科病理病態学
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Yasuda Masanori
Department of Pathology, Saitama Medical University International Medical Center
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Osamura Yoshiyuki
東海大学 医学研究科病理病態学
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Umemura Shinobu
Department of Pathology, Tokai University School of Medicine
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Osamura R
Department Of Pathology School Of Medicine Tokai University
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Osamura R
Department Of Pathology Tokai University School Of Medicine
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Takekoshi Susumu
日本獣医畜産大学 獣医学部獣医外科学教室
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Takekoshi Susumu
Department of Pathology, Tokai University School of Medicine
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Tahara Shigeyuki
Department Of Neurosutgery Nippon Medical School
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Katakami H
Miyazaki Medical School Miyazaki Jpn
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Katakami Hideki
宮崎医科大学 内
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Osamura Yoshiyuki
Department of Pathology Tokai University School of Medicine
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Osamura Y
Department Of Pathology Tokai University School Of Medicine
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Itoh Johbu
Department Of Laboratories For Structures And Function Research School Of Medicine Tokai University
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伊東 丈夫
東海大学医学部教育・研究支援センター細胞科学部門
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竹腰 進
東海大学基盤診療学系病理診断学
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Kajiwara Hiroshi
Department of Pathology, Tokai University School of Medicine
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Takekoshi Susumu
和歌山県立医科大学 病理学
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Itoh Johbu
Laboratories For Structure And Function Research Tokai University School Of Medicine
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Murakami Masaru
Department of Obstetrics and Gynecology, Tokai University School of Medicine
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Takekoshi S
Department Of Pathology School Of Medicine Tokai University
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Osamura Y
Department Of Pathology School Of Medicine Tokai University
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Makino Tsunehisa
Departments Of Obstetrics And Gynecology Tokai University
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Makino Tsunehisa
東海大学 医学部産婦人科学
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Osamura R.
Department Of Pathology Tokai University School Of Medicine
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Osamura Robert
Department of Pathology, Tokai University School of Medicine
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Hirasawa Takeshi
Department of Obstetrics and Gynecology, Tokai University School of Medicine
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TERAMOTO Akira
Departments of Neurosurgery, Nippon Medical School
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Muramatsu Toshinari
Department of Obstetrics and Gynecology, Tokai University School of Medicine
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Watanabe Keiichi
Department Of Internal Medicine School Of Medicine Tokai University
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Osamura R.Yoshiyuki
Department of Pathology, Tokai University School of Medicine
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Teramoto Akira
Department Of Neurosurgery Nippon Medical School
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Itoh J
Laboratories For Structure And Function Research School Of Medicine Tokai University
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MIYAMOTO Tsuyoshi
Department of Obstetrics and Gynecology, School of Medicine, Tokai University
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Kakimoto Kochi
Department of Pathology Tokai University School of Medicine
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Fujita Mariko
Department of Pathology, Tokai University School of Medicine
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Miyazawa Masaki
Department of Pathology, Tokai University School of Medicine
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Kumaki Nobue
Department of Pathology, Tokai University School of Medicine
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Fujita Mariko
Department Of Pathology Tokai University School Of Medicine
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SANNO Naoko
Department of Neurosurgery, Tama-Nagayama Hospital, Nippon Medical School
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Sanno Naoko
日本医科大学 脳神経外科
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Sanno N
Department Of Neurosurgery Nippon Medical School
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Watanabe K
Aoba Gakuen
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Tokuda Y
Department Of Surgery Tokai University School Of Medicine
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Teramoto Akira
流山中央病院 脳神経外科
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SHINOZUKA Takao
Department of Gynecology, School of Medicine, Tokai University
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Itoh Johbu
Teaching and Research Support Center Tokai University School of Medicine
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Egashira Noboru
Department of Pathology, Tokai University School of Medicine
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Mikami Mikio
Department of Obstetrics and Gynecology, Tokai University School of Medicine
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KOIZUMI Haruko
Toxicology Research Laboratories, Central Pharmaceutical Research Institute
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TAKAHASHI Akemi
Toxicology Research Laboratories, Central Pharmaceutical Research Institute
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Watanabe Toshiteru
Research Laboratory School Of Medicine Tokai University
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Ishiwata Isamu
聖マリアンナ医科大学 医学部産婦人科
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Ishiwata Isamu
石渡産婦人科病院
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Ishiwata Isamu
東海大学 医学部病理診断学
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Takahashi A
Toxicology Research Laboratories Central Pharmaceutical Research Institute
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Koizumi H
Toxicology Research Laboratories Central Pharmaceutical Research Institute
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Koizumi Haruko
日本たばこ産業
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Sanno Naoko
Department Of Neurosurgery Nippon Medical Sehool
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Itoh Johbu
Cell Science, Teaching and Research Support Center Tokai University School of Medicine
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Itoh Johbu
Laboratories of Structure and Function Research Tokai University School of Medicine
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Takahashi Akemi
Toxicology Research Laboratories Central Pharmaceutical Research Institute
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Itoh Johbu
Department Pathology Of Tokai University School Of Medicine
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Watanabe Keiichi
Aoba Gakuen Junior College
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Saito Kaoru
Department of Obstetrics and Gynecology, Saint Marianna University School of Medicine
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MIYAJIMA Katsuhiro
Toxicology Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc.
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TATENO TORU
Department of Clinical and Molecular Endocrinology, Tokyo Medical and Dental University Graduate Sch
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HIRATA YUKIO
Department of Clinical and Molecular Endocrinology, Tokyo Medical and Dental University Graduate Sch
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Hirabayashi Kenichi
Department of Pathology, Tokai University School of Medicine
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Ishiwata Isamu
Ishiwata Obstetrics and Gynecology Hospital
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Nagata Hidetaka
Department of Pathology, Tokai University School of Medicine
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MIYAKAWA Yoshifumi
Toxicology Research Laboratories, Central Pharmaceutical Research Institute
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伊藤 丈夫
東海大学共同利用研究室
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TERACHI Toshiro
Department of Urology, Kyoto University Graduate School of Medicine
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Miwa Takeshi
Department Of Internal Medicine School Of Medicine Tokai University
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Itoh Yoshiko
Teaching and Research Support Center Tokai University School of Medicine
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Hirata Y
Department Of Clinical And Molecular Endocrinology Tokyo Medical And Dental University Graduate Scho
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YOSHIMURA Shinichi
Department of Neurosurgery, Graduate School of Medicine, Gifu University
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MORI Yusuke
Department of Engineering, Osaka University
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Terachi Toshiro
Department Of Urology Tokai University School Of Medicine
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Terachi Toshiro
東海大学 医学部病理学
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MITOMI Toshio
Department of Surgery, School of Medicine, Tokai University
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Nagata Hidetaka
東海大学 医学部麻酔科
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Nagata Hidetaka
Department Of Pathology Tokai University School Of Medicine
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Mitomi Toshio
Department Of Surgery (division Of Pediatric Surgery) Tokai University School Of Medicine
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Ishiwata Isamu
Ishiwata Gynecologic Hospital
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Itoh Yoshiko
東海大学 教育研究支援センター
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Itoh Yoshiko
Histochemistry Teaching And Research Support Center Tokai University School Of Medicine
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MAEDA Hironobu
Department of Chemistry, Okayama University
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Tateno Toru
Department Of Clinical And Molecular Endocrinology Tokyo Medical And Dental University Graduate Scho
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Miwa T
Tokai Univ. School Of Medicine Kanagawa Jpn
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Matsuno A
Department Of Neurosurgery Teikyo University Ichihara Hospital
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Matsuno Akira
帝京大学ちば総合医療センター 脳神経外科
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MINEMATSU Takeo
Department of Gerontological/Wound Care Nursing, The University of Tokyo
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UTSUNOMIYA Hirotoshi
Department of Strategic Surveillance for Functional Food and Comprehensive Traditional Medicine, Wak
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堤 寛
東海大学医学部病態診断系病理学
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TSUCHIYA KYOICHIRO
Department of Clinical and Molecular Endocrinology, Tokyo Medical and Dental University Graduate Sch
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MINAMI ISAO
Department of Clinical and Molecular Endocrinology, Tokyo Medical and Dental University Graduate Sch
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IZUMIYAMA HAJIME
Department of Clinical and Molecular Endocrinology, Tokyo Medical and Dental University Graduate Sch
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DOI MASARU
Department of Clinical and Molecular Endocrinology, Tokyo Medical and Dental University Graduate Sch
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NEMOTO TETSUO
Department of Clinical Pathology, Tokyo Medical and Dental University Graduate School
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MAE SUNAO
Division of Medicine, Nakano General Hospital
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KASUGA TSUTOMU
Division of Pathology, Nakano General Hospital
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OKI YUTAKA
Department of Medicine, Hamamatsu Medical University
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Miyakoshi Takashi
Department of Pathology, Tokai University School of Medicine
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Miyajima Katsuhiro
Department of Pathology, Tokai University School of Medicine
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Kjiya Hanako
Department of Pathology, Tokai University School of Medicine
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Kitatani Kanae
Department of Pathology, Tokai University School of Medicine
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Iida Tetsuji
Department of Obstetrics and Gynecology, Tokai University School of Medicine
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Shimizu Michio
Department of Pathology, Saitama Medical University International Medical Center
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Hasegawa Jun
Department of Anesthesiology, Tokai University School of Medicine
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Suzuki Toshiyasu
Department of Anesthesiology, Tokai University School of Medicine
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SHODA Toshiyuki
Toxicology Research Laboratories, Central Pharmaceutical Research Institute
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Sasaki Hiroshi
Department of Biological Technology, Faculty of Science and Engineering,Senshu University of Ishinom
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Shima Masanori
東海大学 医学部泌尿器科学
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Shima Masanori
Department Of Urology Tokai University School Of Medicine
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SASAKI Yutaka
Department of Stem Cell Biology and Regenerative Medicine, Graduate School of Medical Science, Kansa
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Itoh Johbu
Department of Pathology, Tokai University School of Medicine
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Hirata Yukio
東京医科歯科大学 大学院分子内分泌内科学
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SHINOHARA OSAMU
Department of Pediatrics, Tokai University School of Medicine
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TOMITA Yuichiro
Department of Pediatrics, Tokai University School of Medicine
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MATSUNO Akira
Department of Neurosurgery, Teikyo University Chiba Medical Center
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YAMADA So
Department of Neurosurgery, Teikyo University Chiba Medical Center
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MURAKAMI Mineko
Department of Neurosurgery, Teikyo University Chiba Medical Center
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Kobayashi Youichi
Department of Medicine, Division of Cardiology, Showa University School of Medicine
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MITANI Fumiko
Department of Biochemistry, School of Medicine, Keio University
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Tokunaga Masatoshi
Department Of Urology Tokai University School Of Medicine
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Tokunaga Masatosi
東海大学 医学部泌尿器科学
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Tokunaga Masatoshi
東海大学医学部附属大磯病院 泌尿器科学
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Usui Yukio
東海大学 医学部泌尿器科学
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Usui Yukio
Department Of Urology Tokai University School Of Medicine
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Usui Yukio
荻窪病院 泌尿器科
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Kobayashi Yasuyuki
Department of Urology, Tokai University School of Medicine
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MIYAKITA HIDESHI
Department of Urology, Tokai University School of Medicine Ooiso Hospital
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KAWAMURA Yoshiaki
Department of Urology, Tokai University School of Medicine
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SHOJI Sunao
Department of Urology, Tokai University School of Medicine
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KONO Takuo
Department of Urology, Tokai University School of Medicine
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MASUDA Aiichiro
Department of Oiso Hospital, Tokai University
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KINOSHITA Hidechika
Department of Urology, Tokai University School of Medicine
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OGAWA Teppei
Health Evaluation and Promotion Center, Tokai University School of Medicine
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HONMA Yasuhiko
Health Evaluation and Promotion Center, Tokai University School of Medicine
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Masuda Aiichiro
東海大学 医学部泌尿器科学
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Masuda Aiichiro
Department Of Oiso Hospital Tokai University
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Masuda Aiichiro
Department Of Urology Tokai University School Of Medicine Tokyo Hospital
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Kinoshita Hidechika
東海大学 医学部泌尿器科学
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Kinoshita Hidechika
Department Of Urology Tokai University School Of Medicine
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Kinoshita Hidechika
Department Of Urology School Of Medicine Tokai University
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Miyakita Hideshi
東海大学医学部附属病院 臨床検査科
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Miyakita Hideshi
Department Of Urology Tokai University School Of Medicine Ooiso Hospital
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Miyakita Hideshi
Department Of Urology School Of Medicine Tokai University
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Mae Sunao
東京医科歯科大学 院分子内分泌内科学
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Mae Sunao
Division Of Medicine Nakano General Hospital
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Honma Yasuhiko
東海大学 医学部泌尿器科学
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Minami Isao
Department Of Clinical And Molecular Endocrinology Tokyo Medical And Dental University Graduate Scho
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Takekoshi Susumu
Department Of Pathology Tokai University School Of Medicine
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Izumiyama Hajime
東京医科歯科大学 大学院内分泌糖尿病代謝内科
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Izumiyama Hajime
Department Of Clinical And Molecular Endocrinology Tokyo Medical And Dental University Graduate Scho
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SHIBUYA Makoto
Department of Pathology, Tokai University Hachioji Hospital
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TSUTSUMI Yutaka
Department of Pathology, School of Medicine, Tokai University
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Kirimura Yukiko
Department of Pathology, Tokai University School of Medicine
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Osamuara Yoshiyuki
Department of Pathology, Tokai University School of Medicine
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HARA Yasushi
Divisions of Veterinary Surgery, School of Veterinary Medicine, Nippon Veterinary and Life Science U
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TESHIMA Takahiro
Divisions of Veterinary Surgery, School of Veterinary Medicine, Nippon Veterinary and Life Science U
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NEZU Yoshinori
Divisions of Veterinary Surgery, School of Veterinary Medicine, Nippon Veterinary and Life Science U
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HARADA Yasuji
Divisions of Veterinary Surgery, School of Veterinary Medicine, Nippon Veterinary and Life Science U
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TAGAWA Masahiro
Divisions of Veterinary Surgery, School of Veterinary Medicine, Nippon Veterinary and Life Science U
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Oki Yutaka
東京慈恵会医科大学 医学部糖尿病･内分泌内科学
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Oki Yutaka
Department Of Medicine Hamamatsu Medical University
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Kono Takuo
Department Of Urology Tokai University School Of Medicine
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Kono Takuo
東海大学 医学部泌尿器科学
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Usui Y
Department Of Urology Tokai University School Of Medicine
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Doi Masaru
東京医科歯科大学 大学院内分泌糖尿病代謝内科
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Doi Masaru
Department Of Clinical And Molecular Endocrinology Tokyo Medical And Dental University Graduate Scho
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Ogawa Teppei
東海大学 医学部泌尿器科学
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Ogawa Teppei
Health Evaluation And Promotion Center Tokai University School Of Medicine
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Ogawa Teppei
Department Of Health Evaluation And Promotion Tokai University School Of Medicine
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Honma Yasuhiko
Health Evaluation And Promotion Center Tokai University School Of Medicine
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Taoda Takahiro
Kitasato Univ. Aomori
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Kasuga Tsutomu
東京医科歯科大学 院分子内分泌内科学
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Kasuga Tsutomu
Division Of Pathology Nakano General Hospital
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Oda Koji
名古屋大学 腫瘍外科
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YOSHITAKE Tomoko
Department of Obstetrics and Gynecology, Specialized Clinical Science, Tokai University School of Me
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ODA Koji
Department of Surgery, Division of Surgical Oncology, Nagoya University, Graduate School of Medicine
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Khanna Ajay
Departments Of Surgery Tokai University School Of Medicine
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Nagashima Tadashi
Department of Neurosurgery, Teikyo University Ichihara Hospital
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Katakami Hideki
Departments Of Medicine Miyazaki Medical College
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Tagawa Masahiro
Nippon Veterinary And Life Sci. Univ. Tokyo
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OYAMA KENICHI
Department of Neurosurgery, Nippon Medical School
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KUROTANI REIKO
Department of Neurosurgery, Nippon Medical School
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Yogo Takuya
Nippon Veterinary And Life Sci. Univ. Tokyo
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Yogo Takuya
Division Of Veterinary Surgery Department Of Veterinary Science Faculty Of Veterinary Medicine Nippo
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Murakami Mineko
Department Of Neurosurgery Ichihara Hospital Teikyo University School Of Medicine
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INADA Kenichi
Department of Pathology, Tokai University School of Medicine
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MATSUI Naruaki
Department of Pathology, School of Medicine, Tokai University
著作論文
- Malignant Gastric Carcinoid Causing Ectopic ACTH Syndrome : Discrepancy of Plasma ACTH Levels Measured by Different Immunoradiometric Assays
- S3-03 Recent progress in laser capture microdissection for molecular histology(Advanced Histochemistry)
- An Up-to-Date Anti-Cancer Treatment Strategy Focusing on HIF-1α Suppression : Its Application for Refractory Ovarian Cancer
- Sevoflurane Stimulates MAP Kinase Signal transduction through the Activation of PKC α and βII in Fetal Rat Cerebral Cortex Cultured Neuron
- Immunohistochemical Analysis of Neuroendocrine (NE) Differentiation in Testicular Germ Cell Tumors (GCTs) : Use of Confocal Laser Scanning Microscopy (CLSM) to Demonstrate Direct NE Differentiation from GCTs
- Screening program of prostate cancer at Tokai University Hospital : Characterization of prostate-specific antigen measurement
- I-B-01 An application of immunohistochemistry and cytochemistry imaging : Three dimensional analysis of nano crystal (Q dot) labeled antibody by confocal laser scanning microscopy (CLSM) and immunoelectronmicroscopy (IEM)(THE 45TH ANNUAL MEETING OF THE JA
- Histopathological Review of Silent Pituitary Somatotroph Adenoma
- Expression of Neuro D1 in Human Nontumorous Pituitaries and Pituitary Adenomas
- Immunohistochemical Analysis of GH-Producing Adenomas : With Special Emphasis on Plurihormonality of Individual Tumor Cells by Double Staining
- Malignant transformation of atypical endometrial hyperplasia after progesterone therapy showing germ-cell tumor-like differentiation
- Immunohistochemical Expression of Type-1 Carbohydrate Antigens : Availability of DU-PAN-2 on Pathological and Clinical Aspects
- Uterine body cancer mass screening at Tokai University Hospital
- Serum carbohydrate antigen elevations in endometrial adenocarcinomas : Characterization of DU-PAN-2 expression as a tumor marker
- Modification of p53 Immunoexpression Associated with Chemotherapy Regimens in Advanced and Refractory Ovarian Cancers(Prof. K Watanabe Memorial Article)
- Coexistence of Corticotroph Adenoma and Thyrotroph Hyperplasia in a Dog(Surgery)
- Expression of Carbohydrate Antigens (SSEA-1, Sialyl-Lewis X, DU-PAN-2 and CA19-9) and E-selectin in Urothelial Carcinoma of the Renal Pelvis, Ureter, and Urinary Bladder
- IIB-01 Expression of Hypoxia-related markers, GLUT-1 and HIF-1 alpha, in the ovarian tumors : association with histology and tumor grade(THE 46TH ANNUAL MEETING OF THE JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY)
- IA-20 Expression analysis of Cocaine- and amphetamine-regulated transcript (CART), leptin, orexin and neuropeptide Y in the smoking-treated rat pituitary and hypothalamus(THE 46TH ANNUAL MEETING OF THE JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY)
- I-C-23 Significance of GLUT-1 expression as a differential and biological marker in thyroid gland tumors(THE 45TH ANNUAL MEETING OF THE JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY)
- Role of Hepatocyte Growth Factor and c-Met Receptor in Neoplastic Conditions of Salivary Glands
- Association of hepatocyte growth factor expression with salivary gland tumor differentiation
- Expression of Bone Matrix Proteins in Malignant Myoepithelioma with Extensive Osteoid Formation Occurring in The Maxilla
- Renal cell carcinoma arising in a long pre-existing angiomyolipoma
- Treatment Strategy for Recurrent and Refractory Epithelial Ovarian Cancer : Efficacy of High-Dose Chemotherapy with Hematopoietic Stem Cell Transplantation
- Utility of Confocal Laser Scanning Microscopy (CLSM) : With Reference to Interpretation in Immunostaining
- Availability of CD10 as a Histopathological Diagnostic Marker
- Mechanisms for Production and Secretion of Hormones in Physiologic and Pathologic Conditions
- Pit-1 Gene Inhibition Using Small Interfering RNAs in Rat Pituitary GH Secreting Cell Line
- Clinical and Histological Prognostic Factors in Axillary Node-Negative Breast Cancer: Univariate and Multivariate Analysis with Relation to 5-Year Recurrence
- Increased phosphorylation of Akt in triple-negative breast cancers
- A Study of 46 Cumulative Breast Cancer Autopsy Cases
- Epithelial Proliferative Lesions and Carcinomas in Fibroadenomas of the Breast
- Lack of Prolactin (PRL) mRNA Expression in Estrogen-treated Rat Mammary Glands
- Expression of Prolactin-Receptor mRNA in Mammary Adenocarcinoma of a F344 Rat
- Expression of PRL mRNA in the lactating rat mammary gland : Effect of ovariectomy
- Olfactory Neuroblastoma Causing Ectopic ACTH Syndrome
- Application of Genetic Engineering Technologies for the Study of Pituitary Development and Neoplasms
- Immunocytochemical Localization of Glutathione-Peroxidase (GSH-PO) and Bcl-2 in the Rat Ventral Prostate
- Immunolocalization of Glutathione-Peroxidase (GSH-PO) in Human Adrenal Gland : Studies on Adrenocortical Adenomas associated with Primary Aldosteronism and Cushing's Syndrome
- Observations of rat adrenocortical glutathione-peroxidase(GSH-PO) : Changes in neonatal, adult and aged
- PRE-EMBEDDING IMMUNOELECTRON MICROSCOPY BY PEROXIDASE-LABELED ANTIBODY METHOD : APPLICATIONS TO ENDOCRINOLOGY (HISTOCHEMISTRY AND CYTOCHEMISTRY OF ENDOCRINE ORGANS)
- BIOCHEMICAL AND IMMUNOHISTOCHEMICAL STUDIES OF GLUTATHIONE PEROXIDASE IN THE RAT ADRENAL CORTEX
- Ultrastructural Localization of Anterior Pituitary Hormones (Prolactin, ACTH LH) in the Stimulated and Suppressed Rat Pituitaries
- Expression of Transcriptional Factors of GATA4, GATA6 and SF-1 in the Developmental Process of Rat Adrenal Cortex; the Possible Contribution of GATA4 in Limited Expression before Zonal Establishment
- Immunocytochemical Localization of Adrenodoxin and Adrenodoxin Reductase in Hypophysectomized and ACTH Administered Rat Adrenal Corteces
- Glutathione-Peroxidase (GSH-PO) and Androgen Action in Prostate : An Immunohistochemical Study
- Immunolocalization of Glutathione-Peroxidase (GSH-PO) in the Steroid-Producing Organs and Prostate
- Therapeutic strategy targeting the mTOR-HIF-1α-VEGF pathway in ovarian clear cell adenocarcinoma
- Alterations of myoepithelial cells in the rat mammary gland during pregnancy, lactation and involution, and after estradiol treatment
- Involvement of Lipid Peroxidation in the Alteration of Protein Kinase C Signaling
- P-23-B New Hypothesis of the Antigen Retrieval Mechanism by High-Temperature Heating in Irnmunohistochemistry of Ki-67 and Proliferating Cell Nuclear Antigen(PCNA)(THE JOINT MEETING OF THE 44TH ANNUAL MEETING OF THE JAPAN SOCIETY OF HISTOCHEMISTRY AND CYT
- Expression of chromogranin/secretogranin mRNA in spontaneous mammary tumors in aging Fischer-344 rats
- Apoptotic Cells in the Human Endometrium and Placental Villi : Pitfalls in Applying the TUNEL Method
- Changes in ultrastructural localization of prolactin (PRL) in the rat estrogen-induced PRL secreting tumors by Bromocriptine (Br)
- Immunohistochemical localization of ACTH and related peptides in the rat pituitary gland and hypothalamus (2) : Comparative studies by adrenalectomy and ACTH administration
- Correlation between Glutathione-peroxidase (GSH-PO) and Lipid Peroxides in the Adrenal Cortex (6)
- Functional molecular morphology of anterior pituitary cells, from hormone production to intracellular transport and secretion
- Endocrine System and Endocrine Disrupting Chemicals (EDCs)