腎癌患者におけるhaptoglobinの変動

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The authors have examined levels of and changes in serum haptoglobin in 33 cases with renal cell carcinoma. Immunoelectrophoresis and the single radial immunodiffusion method were used to clarify the ability of serum haptoglobin to detect the said carcinoma. Results obtained were as follows: 1) The mean with standard deviation of concentration of serum haptoglobin from the 33 cases was 317±199 mg/dl, 28 were above the normal mean. A remarkable rise in haptoglobin level was found in patients with advanced cancer. 2) Haptoglobin phenotypes in the immunoelectrophoretic patterns were: 4 cases of Hp1-1, 9 cases of Hp2-1 and 17 cases of Hp2-2. Serum haptoglobin phenotype distribution was normal. The mean serum haptoglobin concentration with standard deviation in each phenotype was 402±219 mg/dl. in Hp2-2, 376±163 mg/dl. in Hp2-1 and 230±114 mg/dl. in Hp1-1.
社団法人日本泌尿器科学会の論文