誘導マクロファージの培養中の形態学的分類とその機能について

概要

論文の詳細を見る
Peritoneal macrophages were induced by Peptone or LPS, isolated and cultured for five hours. The morphology of the macrophages was observed during the culure period. We morphologically classified the macrophage cultures into three distinct types : round type(A), long type(B), and flat type(C). Then each type cell was characterized by some functional markers as the phagocytosis and the Fc receptor. The results obtained were as follows ; The proportion of the A type macrophage to total one decreased in the course of culture period, while those of the B or the C type cell increased, regardless of the inducers (Peptone or LPS). Throughout the culture period, the proportion of the C type cell were higher in the case of the induction by LPS than in the case of Peptone, but the reverse result was obtained in that of the A type cell. Both the proportion of the phagocytic cells and that of the Fc receptor positive cells were the greatest in the C type macrophage.
九州歯科学会の論文
1984-04-25