醗酵タンクのスケールアップに関する研究 : (第2報)酸素移動速度

概要

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Studies on the scale-up of fermenters based on the oxygen transfer rate were carried ou, and the following results were obtained. (1) The correlation between k_d and process variables was checked, and the following was obtained by a modification of Fukuda's equation : [numerical formula] The above equation had a good correlation with data from widely different vessels. (2) In Cooper's equation [numerical formula] δdecreased as the operating volume increased ; δseemed to be a function of operating volume. Cooper's equation was modified as follows, showing a good correlation : [numerical formula] where W is mechanical work done by air on the liquid in the fermenter. (3) At different prossures, as long as the volumetric air flow rate is constant, both the volumetric mass transfer coefficients and gas-liquid interfacial areas remained constant. (4) From the results of the previous and present reports, air flow rate can be determined on a volumetric basis in agitated gas-liquid contactors at various pressures.
社団法人日本生物工学会の論文