Measurement of Cholesterol Ester Hydroperoxides of High and Combined Low and Very Low Density Lipoprotein in Human Plasma
スポンサーリンク
概要
- 論文の詳細を見る
The cholesterol ester (CE) hydroperoxides (HPO) were measured in high density lipoprotein (HDL) and combined low and very low density lipoproteins (LDL + VLDL) by a high pressure liquid chromatography with a post column detection system using diphenyl-1-pyrenylphosphine. Human plasma lipoproteins were fractionated from 2 ml of plasma with dextran sulfate and Mg^<2+> to each fraction from which CE-HPO was extracted with n-hexane. The fractionation had no influence on the CE-HPO values in a sample. The relative standard deviations of the CE-HPO were 5. 4% (n = 6) from the HDL fraction and 4. 8% (n = 5) from the LDL + VLDL fraction. The CE-HPO were 6. 8 ± 2. 6 nM (in HDL) and 20. 0 ± 5. 6 nM (in LDL + VLDL) from 10 fresh human plasma samples. The method was used to follow the increase and decrease of CE-HPO in each lipoprotein fraction by the incubation of fresh plasma spiked with dilinoleoyl phosphatidylcholine hydroperoxide.
- 社団法人日本農芸化学会の論文
- 1994-02-23
著者
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大類 洋
横浜薬科大学
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大類 洋
東北大学農学部
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大類 洋
東北大・農
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AKASAKA Kazuaki
Department of Applied Biological Chemistry, Faculty of Agriculture, Tohoku University
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OHRUI Hiroshi
Department of Applied Biological Chemistry, Faculty of Agriculture, Tohoku University
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MEGURO Hiroshi
Department of Applied Biological Chemistry, Faculty of Agriculture, Tohoku University
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Ohrui Hiroshi
Department Of Applied Biological Chemistry Faculty Of Agriculture Tohoku University
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Meguro H
Tohoku Fukushi University
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Meguro H
Department Of Applied Biological Chemistry Faculty Of Agriculture Tohoku University
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大類 洋
東北大学 農
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Ohrui Hiroshi
Department Of Biological Chemistry Faculty Of Agriculture Tohoku University
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Misono Haruo
Department Of Bioresources Science Faculty Of Agriculture Kochi University
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Meguro Hiroshi
Department Of Agricultural Chemistry Faculty Of Agriculture University Of Tokyo
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Moriyama Hideaki
Japan Synchrotron Radiation Research Institute (JASRI)
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