p53- and LET-Dependent Cell Death Induced by Radiation plus Hyperthermia in Human Sauamous Cell Carcinoma (SAS) Transfected with mp53^<Trp248> Gene

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概要

• 論文の詳細を見る
• 日本放射線影響学会の論文

著者

• MAJIMA Hideyuki

  Int. SpaceRadiation Lab., NIRS

• TAMAMOTO Tetsuro

  Depts. Oncoradiol, Radiol

• TAKAHASHI Akihisa

  Depts. Biol. , Nara Med Univ.

• OHNISHI Ken

  Depts. Biol. , Nara Med Univ.

• OHNISHI Takeo

  Depts. Biol. , Nara Med Univ.

• FURUSAWA Yoshiya

  Int. Space Radiat. Lab., Nat. Inst. Radiol. Sci.

• Tamamoto Tetsuro

  高井病院 放射線科

• Furusawa Yoshiya

  高エネルギー加速器研究機構物質構造科学研究所

• Furusawa Yoshiya

  Div. Of Accelerator Res. Natl. Inst. Of Radiol. Sci.

関連論文

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• High LET radiation enhances apoptosis in mutated p53 cancer cells through Caspase-9 activation
• Time Course and Spacial Distribution of UV Effects on Human Skin in Organ Culture
• Reversed dose-rate effect of high LET radiation in mutation induction
• Induction of Micronuclei in Germinating Onion Seed Root Tip Cells Irradiated with High Energy Heavy Ions
• Heavy ion CT system based on measurement of residual range distribution
• Heavy Ion CT Reconstructed from Residual Range Distribution Measured by Range Shifter and Fluoroscopy System
• Sensitometric Properties in Heavy Ion Radiography
• Residual range distribution measured by heavy ion radiography
• Study of the ^7Be (p,γ)^8B Reaction with the Coulomb Dissociation Method
• Inhibition in a microgravity environment of the recovery of Escherichia coli cells damaged by heavy ion beams during the NASDA ISS Phase I Program of NASA Shuttle/Mir Mission No. 6
• A Comparison of Biological Responses of Human Tumor Cells After Irradiation with Heavy Ions and Neutrons
• Proton dosimetry intercomparison based on the ICRU protocol
• Responses of total and quiescent cell populations in solid tumors to carbon ion beam irradiation (290 MeV/u) in vivo
• Dose response relations in acute cell death of pancreatic islets after irradiation of golden hamster with X-ray ,7OMeV proton and 290MeV carbon beams.
• LET spectra of HZE particle beams in a tissue-equivalent material
• Measurements of HIMAC Therapy Beam Qualities
• Protective Effects of Melatonin Against Low- and High-LET Irradiation
• Repair of Skin Damage During Fractionated Irradiation with Gamma Rays and Low-LET Carbon Ions
• Biological Gain of Carbon-ion Radiotherapy for the Early Response of Tumor Growth Delay and against Early Response of Skin Reaction in Mice
• 269 Significance of beta term in carbon-ion radiotherapy(Bases of radiotherapy, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 265 Relationship between RBE values of Carbon Ion and Tumor Growth Rate(Bases of radiotherapy, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 258 Different Responses of Malignant Melanomas and Squamous Cell Carcinomas to X-rays and Heavy-ion Beams-II(Bases of radiotherapy, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Radioprotective Effects of Beer on Radiation-Induced Acute Toxicity in Mice
• Dependence of Gut-crypt Sensitivity on the Time Interval between Two Fractions of Carbon Ion Radiation
• Tumor Growth Rate and RBE values of high LET Carbon Ions
• Dependence of Carbon-Ion RBE on Dose Size -Difference between Skin and Tumors
• Different Responses of Malignant Melanomas and Squamous Cell Carcinomas to X-rays and Heavy-ion Beams
• Synthesis and Evaluation of 4-Bromo-1-(3-[^F]fluoropropyl)-2-nitroimidazole with a Low Energy LUMO Orbital Designed as Brain Hypoxia-Targeting Imaging Agent
• RBE of Carbon Ions for Tumor Growth Delay
• Fractionated irradiation with carbon ions induced resistance in mouse gut crypt cells
• Relative Biological Effectiveness of the 235 MeV Proton Beams at the National Cancer Center Hospital East
• Effects of sequentially mixed LET on tumor growth delay
• Fractionated irradiation with carbon ions to gut intestinal crypt cells
• Spectra of Linear Energy Transfer vs. Relative Biological Effectiveness for Accelerated Heavier Ions upon Clonogenic Survival of V79 Cells
• Analysis of Mutations in the Human HPRT Gene induced by High LET Heavy-ion Irradiation
• Mechanisms of Interphase-Death Induction for CHO Cells Exposed to Accelerated Heavy-Ions
• RBE and OER for Cell Killing upon V79 Cells by Heavy-Ion Beams at a Very High LET Region
• Analysis of Mutations in the Human HPRT Gene Induced by Heavy-ion Irradiation II
• LET Dependence of Interphase Cell-Death Induction by Accelerated Heavy-Ions
• Exploration of 'Over Kill Effect' of High-LET Ar-and Fe-ions by Evaluating the Fraction of Non-hit Cell and Interphase Death
• Heavy-Ion Microbeam System at JAEA-Takasaki for Microbeam Biology
• Dosimetry for heavy-ion radiation fields of argon, iron and kripton beams.
• Hyperthermic Enhancement of Tumor Growth Inhibition by Carbon-ions and X-rays in Transplantable Esophageal Cancer
• p53- Dependent Hyperthermic Enhancement of Cell Killing by Radiations in Human Glioblastoma Cells (A-172/wtp53) Transfected with mp53 Gene.
• Hyperthermic Synergism Depends on p53-status in Carbon-ion Beam-irradiated Human Glioblastoma Cells
• LET Dependence for Somatic Mutation Cross Section of Drosophila Irradiated with Heavy Ion Beams
• LET Dependence for Induction of Drosophila Somatic Mutations Irradiated with Heavy Ion Beams.
• LET, cell cycle dependence for mutation induction and spectrum in HPRT locus
• Cell Cycle and LET Dependence for Radiation-induced Mutation : A Possible Mechanism for Reversed Dose-rate Effect
• Depth Encoding of Point-of-Interaction in Thick Scintillation Cameras
• Effects of fractionated irradiation with carbon ions on the NFSa fibrosarcoma in mice
• Biological Intercomparison Using Gut Crypt Survivals for Proton and Carbon-Ion Beams
• Heavy ion radiography
• Correlation with cell death and chromatin damage by accelerated carbon ion beams
• Verification of ^C-290 MeV/u Tlieraputic Beams for HIMAC Clinical Trial using Mammalian cells
• The uniformity of the biological dose accelerated carbon ion beams with the spread out Bragg peak.
• Development of multichanel Ion Chamber for measurement of 3 dimensional dose Distributions of Heavy-Ion Therapeutic Beam in patients
• Reconstruction of Dose Calculation on CT-Image from Dose Distribution in Water Phantom
• A Proton Dose Calculation Code for Treatment Planning Based on the Pencil Beam Algorithm
• Analysis of the Penumbra for Uniform Irradiation Fields Delivered by a Wobbler method
• Comparative study of He, C, Ne and Ar beams for heavy-ion radiation therapy : Motivation and preliminary result of the comparison -
• Enhancement of radio-sensitivity by NaCl in human cancer cells transfected with mutant p53 gene
• LET-Dependence of Wing-hair and Eye-color Mosaic Spots Inductions at the Somatic Cells of Drosophila Larva Irradiated with 12C (290MeV/u) Ion Beams
• Expression of VEGF mRNA by irradiation with X-ray and heavy-ion beam
• DNA strand breaks induced by heavy ions near the Bragg peak.
• Enhancement of Radiation Sensitivity by Glycerol in Human Cultured Anaplastic Thyroid Carcinoma
• The cell killing and DNA breakage induced by heavy-ion beams
• Quantitative Analysis of Isolated and Clustered DNA Damage Induced by Gamma-rays, Carbon Ion Beams, and Iron Ion Beams
• 202 Quantitation of DNA damage induced by high LET particles(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Distribution of Heavy Ion-Induced G2 Chromatin Damage and Repair in Human Fibroblast Cells
• Heavy-ion Induced Initial G2-chromosome aberrations and Repair Kinetics of Normal Human Fibroblasts
• RBE for scid cells irradiated with high LET radiations
• Repair Kinetics of DNA-DSB Induced by X-rays or Carbon Ions under Oxic and Hypoxic Conditions
• Enhancement of radiation or heat sensitivity by wortmannin
• Evaluation of Indirect Effects in the Inactivation of Human HL-60 Cells Using Dimethylsulfoxide as a Scavenger of OH Radicals
• Different inducibility of radiation- or heat-induced p53-dependent apoptosis after acute or chronic irradiation in human squamous cell carcinoma cells
• Cell cycle and LET dependence for 6-thioguanine-resistant mutation induced by heavy ion beam in mouse L5178Y cells
• 198 LET dependence of Oxidative DNA Damage Induced by Heavy Ions under Hypoxic Condition(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Synergistic Effect by Heavy-Ion Beams and a Hypoxic Sensitizer on Repreductive Death and Apoptosis of V79 Cells
• Enhancement of radio-sensitivity by glycerol that restores mutant p53 to wild type-p53 function
• p53- and LET-Dependent Cell Death Induced by Radiation plus Hyperthermia in Human Sauamous Cell Carcinoma (SAS) Transfected with mp53^ Gene
• nteraction Between Ion Beam and X-ray on Radiobiological Effects II
• DNA Array Analysis of Radiation-induced Gene Expression about Apoptosis-related Genes
• Radiosensitization by Inhibiting Survivin in Human Hepatoma HepG2 Cells to High-LET Radiation
• Early skin reactions after fractionated irradiation of 290MeV/u Carbon- 12
• Enhancement of X-ray-induced apoptosis by lonidamine
• Age-Related Decrease in the Induction of HSP72 by Heat in Human Skin.
• High LET Radiation Enhances Nocodazole Induced Cell Death in HeLa Cells through Mitotic Catastrophe and Apoptosis
• Visualization of Heavy Ion Tracks by Labeling 3'-OH Termini of Induced DNA Strand Breaks
• Radioadaptive response in scid mice
• Effects of FractionalIrradiation of Carbon Ions for Survival and Mutation Frequency on Mammalian Cells

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