BINDlNG CAPACITY OF SEX-HORMONE-BlNDING GLOBULlN AND FREE TESTOSTERONE DETERMlNATION IN EVALUATION OF HIRSUTE WOMEN
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概要
- 論文の詳細を見る
To investigate the relation between free testosterone (T) and binding capacity of sex-hormonebinding globulin (SHBG-BC) and a degree of hirsutism, 34 women were classifled into 3 groups according to the criteria of Ferriman and Gallway on the degree of the hirsutism ; 11 patients with a total score of 1 to 3 (group 1), 8 patients with a total score of 4 to 10 (group 2), and 15 patients with a total score of 11 or more (group 3). Total plasma T, SHBG-BC, and free plasma T were measured in each group, and they were compared with those of controls. In groups I and 2, mean levels of total T were slightly higher than in controls but the differences were not significant. Total T Ievels were extremely elevated in group 3. Mean level of SHBG-BC in group I was slightly lower than in controls but was not statistically significant. SHBG-BC was drastically reduced in groups 2 and 3. The percent free T Ievels and free T concentrations were significantly higher than those of controls in groups 2 and 3, but not in group 1. The iresults suggested that decreased SHBG-BC and increased free T might be the cause of hirsutism in women with normal total T levels.
- 社団法人日本産科婦人科学会の論文
- 1985-03-01
著者
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MIZUTANI Shigehiko
Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine
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MATSUI NOBUO
Department of Endocrinology and Metabolism, The Research Institute of Environmental Medicine, Nagoya
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Miyamoto Norihiro
Department Of Endocrinology And Metabolism The Research Institute Of Environmental Medicine Nagoya U
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Tomoda Yutaka
Department Of Obstetrics And Gynecology Nagoya University School Of Medicine
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Tomoda Yutaka
Department Of Biopharmaceutics Kyoto Pharmaceutical University
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SUGANUMA NOBUHIKO
Department of Obstetrics and Gynecology, Nagoya University School of Medicine
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Wu M
Department Of Obstetrics And Gynecology Nagoya University Branch Hospital Nagoya
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MASAHASHI Tetsuo
Department of Obstetrics and Gynecology, Nagoya University, Branch Hospital, Nagoya
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OHSAWA Masami
Department of Obstetrics and Gynecology, Nagoya University, Branch Hospital, Nagoya
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ASAI Mitsuoki
Department of Obstetrics and Gynecology, Nagoya University, Branch Hospital, Nagoya
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ICHIKAWA Yayoi
Department of Obstetrics and Gynecology, Nagoya University, Branch Hospital, Nagoya
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NARITA Osamu
Department of Obstetrics and Gynecology, Nagoya University, School of Medecine, Nagoya
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WU Ming-chan
Department of Obstetrics and Gynecology and Medicine, Nagoya University School of Medicine
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Matsui N
Department Of Obstetrics And Gynecology And Research Institute Of Environmental Medicine Nagoya Univ
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Mizutani S
Department Of Obstetrics And Gynecology Nagoya University School Of Medicine
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Matsui Nobuo
Department Of Endocrinology And Metabolism The Research Institute Of Environmental Medicine Nagoya U
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Mizutani Shigehiko
Department Of Obstetrics And Gynaecology Nagoya University Graduate School Of Medicine
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Matsul Nobuo
The Research Institute Of Environmental Medicine Nagoya University
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Ohsawa Masami
Department Of Obstetrics And Gynecology Nagoya University School Of Medicine
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Narita Osamu
Department Of Obstetrics And Gynecology Nagoya University School Of Medicine
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Asai Mitsuoki
Department Of Obstetrics And Gynecology Nagoya University School Of Medicine
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Ichikawa Yayoi
Department Of Obstetrics And Gynecology Nagoya University Branch Hospital Nagoya
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Mizutani Shigehiko
Department Of Obstetrics And Gynaecology Nagoya University School Of Medicine
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Tomoda Yutaka
Department Of Obstetrics And Gynecology And Research Institute Of Environmental Medicine Nagoya Univ
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Masahashi Tetsuo
Department Of Obstetrics And Gynecology Nagoya University School Of Medicine
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Suganuma N
Toyohashi Municipal Hospital Toyohashi Jpn
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Suganuma Nobuhiko
Department Of Obstetrics And Gynecology Nagoya University School Of Medicine
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Suganuma Nobuhiko
Infertility Center Toyohashi Municipal Hospital
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Matsui Nobuo
Department Of Endocrinology And Metabolism The Research Institute Of Environmental Medicine Nagoya U
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Narita Osamu
Department Of Obstetrics And Gynaecology Nagoya University School Of Medicine
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Suganuma Nobuhiko
Department of Human Health Science, Graduate School of Medicine, Kyoto University
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Ichikawa Yayoi
Department of Cardiology, Tokyo Women's Medical University
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