SUCCESSFUL PREGNANCIES IN PATIENTS WITH HYPERPROLACTINEMIA : CLINICAL AND ENDOCRINOLOGICAL STUDIES ON MOTHERS AND BABIES
スポンサーリンク
概要
- 論文の詳細を見る
高プロラクチン血症を示した患者の妊娠・分娩例において,プロラクチン産生下垂体腫瘍に対する妊娠・授乳の影響を研究するため,経時的な血中プロラクチンの測定および神経学的検査を行った.また,胎児・新生児の発育に対する母体高プロラクチン血症および妊娠初期に投与されたプロモクリプチン治療の影響を調べるため,新生児の先天異常の有無,生後2年間までの精神・身体発達を追跡調査した.99人の高プロラクチン血症性無月経患者に対し,下垂体腺腫摘除術,プロモクリプチン療法,および両者の併用治療を行った結果,34例が妊娠し,43人の生児を得た.妊娠中に尿崩症および急性視野障害を示した2例を除き,ほぼ全例が異常なく経過し,分娩した.授乳停止後,3例を除き血中プロラクチン値は,妊娠前より低値となった.さらに,機能性高プロラクチン血症と診断された例において,妊娠分娩後に,下垂体腺腫の発生を疑わしめた例はなかった.これらの結果は,妊娠・授乳によって下垂体腫瘍の増大,あるいは活性化を起こさせることがないことを示唆するものといえる.新生児は,すべて外表奇型などは認められず,出生後2年間の発育調査においても異常が認められず,母体の高プロラクチン血症,あるいは妊娠初期におけるプロモクリプチン療法は,胎児・新生児の発育に影響を与えないものと思われる.
- 社団法人日本産科婦人科学会の論文
- 1983-04-01
著者
-
GOTO Takashi
Department of Gastroenterology, Akita University School of Medicine
-
SUZUKI Masatoshi
Department of Veterinary Physiology, Veterinary Medical Science, The University of Tokyo
-
Tomoda Yutaka
Department Of Obstetrics And Gynecology Nagoya University School Of Medicine
-
Tomoda Yutaka
Department Of Biopharmaceutics Kyoto Pharmaceutical University
-
KUWAYAMA AKIO
Department of Neurosurgery, Nagoya National Hospital
-
SUGANUMA NOBUHIKO
Department of Obstetrics and Gynecology, Nagoya University School of Medicine
-
Kuwayama Akio
Department Of Neurosurgery Matsunami General Hospital
-
Kuwayama Akio
Department Of Neurosurgery Nagoya University School Of Medicine
-
NARITA Osamu
Department of Obstetrics and Gynecology, Nagoya University, School of Medecine, Nagoya
-
KAGEYAMA Naoki
Department of Neurosurgery, Nagoya University school of Medicine
-
Goto Takashi
Department Of Gastroenterology Akita University School Of Medicine
-
Narita Osamu
Department Of Obstetrics And Gynecology Nagoya University School Of Medicine
-
Kageyama Naoki
Department Of Neurosurgery Nagoya University School Of Medicine
-
Kageyama Naoki
Department Of Neurosurgery Kishiwada City Hospital
-
Suzuki Masatoshi
Department Of Cardiology Teikyo University School Of Medicine
-
Tomoda Yutaka
Department Of Obstetrics And Gynecology And Research Institute Of Environmental Medicine Nagoya Univ
-
Suganuma N
Toyohashi Municipal Hospital Toyohashi Jpn
-
Suganuma Nobuhiko
Department Of Obstetrics And Gynecology Nagoya University School Of Medicine
-
Suganuma Nobuhiko
Infertility Center Toyohashi Municipal Hospital
-
Goto Takashi
Department Of Gastroenterology Akita University Graduate School Of Medicine
-
Goto Takashi
Department Of Obstetrics And Gynecology Nagoya University School Of Medicine
-
Suzuki Masatoshi
Department Of Obstetrics And Gynecology Nagoya University School Of Medicine
-
Narita Osamu
Department Of Obstetrics And Gynaecology Nagoya University School Of Medicine
-
Goto Takashi
Department of Applied Chemistry, Faculty of Engineering
-
SUZUKI MASATOSHI
Department of Anatomy, Jikei University School of Medicine
-
Suganuma Nobuhiko
Department of Human Health Science, Graduate School of Medicine, Kyoto University
関連論文
- Sex difference in the liver of hepatocyte-specific Pten-deficient mice : A model of nonalcoholic steatohepatitis
- リポソーム・ペプチド・DNA複合体は精子ベクター法による遺伝子導入効率を向上する
- ESTABLISHMENT OF HYBRIDOMAS SECRETING MONOCLONAL ANTIBODIES TO PLACENTAL ALKALINE PHOSPHATASE AND DEVELOPMENT OF AN ENZYME IMMUNOASSAY FOR ITS DETERMINATION
- EFFECT OF β_2-STIMULANT ON UTERO-UMBILICAL BLOOD FLOW IN NORMAL AND GROWTH RETARDED FETUSES
- FREQUENCY OF CHROMOSOMALLY UNBALANCED GAMETES IN MALE AND FEMALE HAMSTERS HETEROZYGOUS FOR RECIPROCAL TRANSLOCATION
- Desmopressin Stimulation Test for Diagnosis of ACTH-Dependent Cushing's Syndrome
- 新生ラット視床下部における性ステロイド依存性遺伝子の発現解析
- 性腺刺激ホルモン放出ホルモンニューロンに緑色蛍光タンパク質を発現するトランスジェニックラットの作出
- Preoperative Treatment of Growth Hormone-Produsing Pituitary Adenoma with Continuous Subcutaneous Infusion of Octreotide
- Direct Effects of Estradiol and Tamoxifen on Gene Expressions of Inhibin α-and βA-Subunits in Rat Granulosa Cells In Vitro
- SPIRONOLACTONE THERAPY FOR HYPERANDROGENIC ANOVULATORY WOMEN : CLINICAL AND ENDOCRINOLOGICAL STUDY
- BINDlNG CAPACITY OF SEX-HORMONE-BlNDING GLOBULlN AND FREE TESTOSTERONE DETERMlNATION IN EVALUATION OF HIRSUTE WOMEN
- A-60. Experimental Stroke and Reconstructive Surgery(Part 2)The effect of Alpha Methyl Tyrosine
- A-11. Cerebral Vasospasm and Vasoactive Amines
- Bony lnvasion of lntracranial Meningioma with Remarks to Recurrences
- A Prospective Study on the Relationship between Intrapartum Maternal Group-B Streptococcal Concentration and Signs of Infection in Neonates
- Elevation of Plasma Atrial Natriuretic Peptide in a Neurosurgical Patient with the Syndrome of Inaapropriate Secretion of Antidiuretic Hormone : Case Report
- SUCCESSFUL PREGNANCIES IN PATIENTS WITH HYPERPROLACTINEMIA : CLINICAL AND ENDOCRINOLOGICAL STUDIES ON MOTHERS AND BABIES
- Coronary intervention in diabetic patients : Current perspective and the future
- Expression of Syndecan-1 and -3 during Embryogenesis of the Central Nervous System in Relation to Binding with Midkine^1
- Decreased renal expressions of heat shock protein-72 and -25 are associated with renal dysfunction in biliary cirrhotic rats
- Epimorphin expression and stellate cell status in mouse liver injury
- Genipin prevents fulminant hepatic failure resulting in reduction of lethality through the suppression of TNF-α production
- Gabexate mesilate, a synthetic protease inhibitor, attenuates carbon tetrachloride-induced liver injury in rats
- Expression of a 72-kDa heat shock protein, and its cytoprotective function, in gastric mucosa in cirrhotic rats
- The expression of Fas and Fas ligand, and the effects of interferon in chronic liver diseases with hepatitis C virus
- MECHANICAL STRETCH INCREASES PRODUCTION OF MMP1 AND DECREASES PRODUCTION OF TIMP1 AND TIMP2 IN HEPATIC STELLATE CELLS
- Laparoscopic Findings in Primary Sclerosing Cholangitis
- Effect of dibutyryl cyclic AMP on phagocytosis and production of nitric oxide and tumor necrosis factor-α in cultured rat Kupffer cells
- Primary Biliary Cirrhosis Associated with Membranous Glomerulonephritis
- Giant Hepatic Biloma Following Transcatheter Oily Chemoembolization in a Patient with Hepatic Metastases from Malignant Pheochromocytoma
- Synthesis and Release of Glycosylated Prolactin in Transfected Cells with human Prolactin Complementary Deoxyribonucleic Acid
- MEASUREMENT OF HUMAN PROLACTIN MESSENGER RNA IN DECIDUAL TISSUES USING COMPLEMENTARY DNA PROBE CLONED IN M13mp9 BACTERIOPHAGE
- Evaluation of Coronary Stents In Vitro With CT Angiography : Effect of Stent Diameter, Convolution Kernel, and Vessel Orientation to the Z-Axis
- Imaging of In-stent Stenosis Using 16-slice Computed Tomography : In Vitro Study with a Specially-made Phantom(X-ray/CT/MRI/DSA 2 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Assessment of Plaque Components in Chronic Total Occlusion by 16-slice Computed Tomography : Impact to the Crossability of CTO Lesion(Coronary Revascularization, PTCA/Stent/DCA/Rotablator/New Device 13 (IHD), The 69th Annual Scientific Meeting of the Japa
- PE-312 Three-dimensional Intravascular Ultrasonic Assessment of the Mechanism of Lumen Reduction of the Saphenous Vein Grafts after Coronary Artery Bypass Surgery(Cardiovascular Surgery/CABG 3 (IHD) : PE53)(Poster Session (English))
- PE-195 The Effect of Acoustic Output Power on Image Enhancement and Attenuation in Contrast Echocardiography(Echo/Doppler 9 (I) : PE33)(Poster Session (English))
- Early Detection of Doxorubicin-Induced Myocardial Damage by Ultrasound Tissue Characterization With Integrated Backscatter
- Modulation of oxidative burst of neutrophils by doxycycline in patients with acute myocardial infarction
- Increased leukocyte activity as a predictor for flow-limiting coronary lesions in patients with angina pectoris
- Regulation of Prolactin Gene Expression in Rats
- Adrenal Insufficiency after Incomplete Resection of Pituitary Macrocorticotropinoma of Cushing's Disease: Role of High Molecular Weight ACTH
- EFFECTS OF PREGNANCY, DELIVERY AND LACTATION IN HYPERPROLACTINEMIA WITH PROLACTIN PRODUCING PITUITARY ADENOMA
- Longitudinal Study of Patients with Idiopathic Isolated TSH Deficiency : Possible Progression of Pituitary Dysfunction in Lymphocytic Adenohypophysitis
- Reproductive Phenotypes in Mice with Targeted Disruption of the 20α-Hydroxysteroid Dehydrogenase Gene
- Negative C-reactive protein in children with bacterial infection
- Factors Influencing an Ultrasound-Estimated Bone Mass in Postmenopausal Women
- Characterization of GH Pulsatility in Male Shiba Goats : Effects of Postpubertal Castration and KP102
- Expression of Ovarian 20α-Hydroxysteroid Dehydrogenase in Rat Thymus
- EXPRESSION OF 20α - HYDROXYSTEROID DEHYDROGENASE IN RAT THYMUS
- ROLE OF GRANULIN THE PROCESS OF SEXUAL DIFFERENTIATION OF THE RAT BRAIN
- Hypothalamic Gonadotropin-Releasing Hormone Gene Expression during Rat Estrous Cycle
- Expression of Asialoglycoprotein Receptor in Human Fetal Liver
- Conservative Handling of the Uterus in a 10-Week Cervical Pregnancy Case
- Supra- and Extrasellar Pituitary Microadenoma as a Cause of Cushing's Disease
- マウス20α-水酸化ステロイド脱水素酵素ゲノムDNAのクローニングとその遺伝子座の決定
- ラット卵巣におけるグラニュリン前駆体蛋白(アクログラニン)の卵子特異的な発現
- Establishment and Characterization of Acquired Resistance to Platinum Anticancer Drugs in Human Ovarian Carcinoma Cells
- 529 Experimental and Numerical Simulations of the Riveting Process by Upset Forging
- Lattice and Radiation Conductivities for Mould Fluxes From the Perspective of Degree of Crystallinity
- IMPROVEMENT OF INTESTINAL ABSORPTION OF PEPTIDES AND PROTEINS BY CHEMICAL MODIFICATION WITH FATTY ACIDS
- 周生期ラットにおけるメトキシクロール暴露が成熟後の生殖機能に与える影響
- Bone Mineral Density in Adult Patients with Turner's Syndrome : Analyses of the Effectiveness of GH and Ovarian Steroid Hormone Replacement Therapies
- ESTABLISHIMENT AND CHARACTERIZATION OF THREE NEW HUMAN GESTATIONAL CHORIOCARCINOMA CELL LINES
- A-82. Revascularization Procedure in Experimental Stroke:Clinical and Pathological Studies
- PURIFICATION OF PLACENTAL ALKALINE PHOSPHATASE AND ITS MONOCLONAL ANTIBODY
- RADIOIMMUNOLOCALIZATION OF MONOCLONAL ANTIBODIES TO HUMAN CHORIONlC GONADOTROPlN IN CHORIOCARClNOMA TRANSPLANTED INTO ATHYMIC MICE
- MONOCLONAL ANTIBODIES TO HUMAN CHORIONIC GONADOTROPIN AND ITS BETA-SUBUNIT
- Alteration of Heme Oxygenase-1 and Heat Shock Protein 72 in the Gastric Mucous in Fasted Streptozotocin-diabetic Rats
- Effects of Gonadotropin, Estrogen, and Progesterone on c-mos Gene Expression in Mouse Oocytes in vivo and in vitro
- Successful Pregnancy after Intracytoplasmic Injection of a Single Testicular Spermatozoon into a Human Oocyte : A Case Report
- ROLE OF SEX-HORMONE-BINDING GLOBULIN AND FREE SEX STEROID HORMONES IN HYPERANDROGENIC ANOVULATION
- CONSERVATIVE SURGERY FOR INFERTILE PATIENTS WITH PELVIC ENDOMETRIOSIS : FACTORS AFFECTING THE PREGNANCY RATE AND EXPECTANCY
- PURIFICATION AND PROPERTIES OF HUMAN PLACENTAL DIPEPTIDYL PEPTIDASE IV
- RELATIONSHIP BETWEEN MATERNAL PROLACTIN LEVELS DURING PREGNANCY AND LACTATION IN WOMEN WITH PITUITARY ADENOMA
- PURIFICATION AND PROPERTIES OF A HUMAN PLACENTAL POST-PROLINE ENDOPEPTIDASE
- A Case of Uterine Choriocarcinoma with Spontaneous Rupture Twenty-Three Years following the Antecedent Pregnancy
- Effects of All-trans Retinoic Acid on Choriocarcinoma Cells in vitro
- Purification and Characterization of 1, 25(OH)_2D_3 Receptor from Human Placenta
- Age-Dependent Changes in Progranulin Expression in the Mouse Brain
- Roles of Progranulin in Sexual Differentiation of the Developing Brain and Adult Neurogenesis
- ラット卵巣におけるグラニュリン前駆体蛋白(アクログラニン)の卵子特異的な発現
- TRANSFORMING GROWTH FACTOR-β1 INDUCES MORPHOLOGICAL CHANGES ACCOMPANIED BY EXTRACELLULAR MATRIX RECONSTITUTION IN CULTURES OF AVIAN RETINAL PIGMENTED EPITHELIAL CELLS
- 周生期ラットにおけるメトキシクロール暴露が成熟後の生殖機能に与える影響
- The relationship between Kuchofuku^【○!R】 and body temperature in X-linked anhidrotic ectodermal dysplasia
- Portal gas in a diabetic patient under pharmacotherapy with an alpha-glucosidase inhibitor : report of a case with emphasis on US findings
- DISSOCIATION OF hCG-RECEPTOR COMPLEX AND DETECTION OF hCG RECEPTORS IN HUMAN CHORIONIC TISSUES
- Involvement of Granulin in Estrogen-Induced Neurogenesis in the Adult Rat Hippocampus
- Involvement of Granulin in Estrogen-Induced Neurogenesis in the Adult Rat Hippocampus
- Age-Dependent Changes in Progranulin Expression in the Mouse Brain
- 46 Effect of Ca-blocker (nifedipine) and dipyridamole on umbilical and uterine arterial blood flow.
- Characterization of the Growth Factor Activity of Amniotic Fluid on Cells from Hematopoietic and Lymphoid Organs of Different Life Stages
- Friction Welding Characteristics of Al-Mg Aluminum Alloy (A5056) and Carbon Steel (S45C)
- 412 Friction Welding Characteristics of Al-Mg Aluminum Alloy (A5056) and Carbon Steel (S45C)
- THE EFFECT OF β_2-ADRENERGIC STIMULANTS ON PROGESTERONE PRODUCTION BY HUMAN PLACENTAL TISSUE IN CULTURE
- PROGNOSTIC SIGNIFICANCE OF NUCLEAR ANALYSIS IN INVASIVE CARCINOMA OF CERVIX PATIENTS TREATED BY PRIMARY RADIATION
- Specific Enzyme Immunoassay for Human Chorionic Gonadotropin using Antibody to the Synthtic Peptide Corresponding to the Carboxyl-Terminal Region of the β-subunit of hCG
- Effects of Cyclophenyl and Clomiphene on Excretion of Urinary LH
- Expression of Syndecan-1 and -3 during Embryogenesis of the Central Nervous System in Relation to Binding with Midkine.