高血圧発症ラットに対する海藻粉末の高血圧抑制

概要

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We prepared dry powders of Kombu (Laminaria japonica) and Nori (Porphyra yezoensis) and examined their preventive effect on blood pressure in spontaneuosly-hypertensive rat. These powders were respectively mixed into a basal powder diet for breeding at a density of 10% and orally given to rats. When we started the treatment at 5 weeks old, before suffering from hypertension, the blood prerssure of the Kombu diet group was kept around 163 mmHg, whereas that of the control diet group increased over 191 mmHg. The Nori diet did not possess such preventive effect. In the treatment at 9 weeks old when the hyoertension just began. The Kombu diet demonstrated a curative effect on the hypertension: 160 mmHg vs. 199 mmHg of the control group at 12 week old (p<0.05). The Nori diet exhibited the curative effect at less extent: 170 mmHg vs. 199 mmHg (p<0.05). It is expected that these diets would have the preventive and corrective effect on clinical hypertension.
熊本大学の論文
2003-11-28