高脂血症ラットに対する海藻粉末の予防効果(I)

概要

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We prepared dry micro-powders of Kombu (Laminaria japonica) and Wakame (Undaria pinnatifida)seaweeds, and examined their effect on blood lipid level in rat. These powders were respectively mixed into a high fat diet at a density of 5% and orally given to rats. To control rats, only the high fat diet was given. When we have treated the rats for 7 weeks, the blood neutral fat level increased up to 35.0 mg/dl and 39.2 mg/dl in the control group and in the Wakame group, respectively. Making a sharp contrast with those, the blood neutral fat level of the Kombu diet group decreased down to 17.4 mg/dl (p<0.01). On the other hand, total cholesteroland HDL-cholesterol levels did not differ among three groups. In confirmatory experiments using 75% high fat diet (25% less fat content than the high fat diet), the results were basically the same. It is expected that the Kombu powder would have the preventive effect on clinical hyperlipidemia.
熊本大学の論文
2004-11-30