<原著>柴胡およびサイコサポニンの研究 : (2)サイコサポニンの抗炎症作用の機序について

概要

論文の詳細を見る
The changes occurred in rat adrenal and thymus by the treatment with saikosaponins, which were intraperitoneally injected for 4 days in the concentration of 5mg/kg/day, 10mg/kg/day or 15mg/kg/day, were studied by weighing and light microscopical observation. The weight of adrenal was increased but the weight of thymus was decreased with the increase of concentration of saikosaponins. The light microscopic observation of cross sections of the adrenals of rats treated with saikosaponins showed the remarkable increase in thickness of cortex associated with reduction of zona glomerulosa, and the diameter of medulla was also increased. In the thymus of rats treated with saikosaponins, the number of lymphoid cells of cortex was significantly decreased and the border line between medulla and cortex was unclear.
近畿大学の論文
1979-03-25